Lysyl oxidase is homologous to the ras recision gene product (rrg), which counteracts the transforming activity of ras . Lysyl oxidase is synthesized as a single polypeptide. Several isoforms of the enzyme may exist. It is purified from bovine aorta and cultured fibroblasts, in addition to other...
Mol. Cell 68, 1016–1016.e1 (2017). CAS PubMed Google Scholar Li, Y. et al. The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate. J. Biol. Chem. 284, 34283–34295 (2009). This study established the biochemical activity of NSD1, ...
(Khib), β-hydroxybutyrylation (Kbhb), succinylation (Ksucc), and lactylation (Kla) have been identified [2,3] (Fig.1). These modifications influence protein structure and modulate their stability, localization, and activity [4]. Based on the chemical properties of lysine modification, ...
SOD activity was determined by spectroscopy using the xanthine oxidase/cytochrome c method (McCord and Fridovich, 1969). The amount of SOD required to inhibit the reduction of cytochrome c by 50% was defined as 1 unit of activity. For the APX assay, leaf discs (about 2 cm2) were homogeni...
the acyltransferase activity of p300 gets weaker with increasing acyl-chain length [23]. Still, p300/CBP was considered to be the major HCT in mammalian cells [24], the p300/CBP mutants with deficient HAT but competent HCT activity substitute the endogenous CBP/p300 to enhance transcriptional ac...
The generation of reactive oxygen species (ROS) in the mutant line was assessed by qRT-PCR analysis of NADPH oxidase (RbohD and RbohF), and by DCFH-DA staining. Cellular levels of ROS in osldc-like 1 leaves were significantly lower than those in the wild-type (WT) rice after exposure ...
Histone demethylation mediated by the nuclear amine oxidase homolog LSD1 Cell (2004) N. Ballas et al. Regulation of neuronal traits by a novel transcriptional complex Neuron (2001) Y.J. Shi et al. Regulation of LSD1 histone demethylase activity by its associated factors Mol. Cell (2005) M....