Lysyl oxidase is homologous to the ras recision gene product (rrg), which counteracts the transforming activity of ras . Lysyl oxidase is synthesized as a single polypeptide. Several isoforms of the enzyme may exist. It is purified from bovine aorta and cultured fibroblasts, in addition to other...
the acyltransferase activity of p300 gets weaker with increasing acyl-chain length [23]. Still, p300/CBP was considered to be the major HCT in mammalian cells [24], the p300/CBP mutants with deficient HAT but competent HCT activity substitute the endogenous CBP/p300 to enhance transcriptional ac...
Mol. Cell 68, 1016–1016.e1 (2017). CAS PubMed Google Scholar Li, Y. et al. The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate. J. Biol. Chem. 284, 34283–34295 (2009). This study established the biochemical activity of NSD1, ...
Full size image The post-SET region of DIM-5 contains three conserved cysteine residues, arranged CXCX4C, that are essential for its histone lysine methyltransferase activity [15]. The structure of DIM-5 in a ternary complex with an H3 K9 peptide and AdoHcy [16] reveals that, as expected ...
The generation of reactive oxygen species (ROS) in the mutant line was assessed by qRT-PCR analysis of NADPH oxidase (RbohD and RbohF), and by DCFH-DA staining. Cellular levels of ROS in osldc-like 1 leaves were significantly lower than those in the wild-type (WT) rice after exposure ...
the acyltransferase activity of p300 gets weaker with increasing acyl-chain length [23]. Still, p300/CBP was considered to be the major HCT in mammalian cells [24], the p300/CBP mutants with deficient HAT but competent HCT activity substitute the endogenous CBP/p300 to enhance transcriptional ac...
Protein lysine demethylases (PKDMs) consist of the lysine-specific demethylase 1 (LSD1) family, which are flavin-dependent monoamine oxidases, and the Jumonji C (JmjC) domain-containing proteins, which are α-ketoglutarate-dependent Fe(ii) dioxygenases. ...