Although the bimodal distribution of protein half-lives in whole blood is satisfactorily explained by distinct turnover rates for circulating plasma and cells, we caution that these half-life estimates may be less precise than those reported for solid tissues. This is because the model assumes that...
blood cells via series of different CRP related mapped genes, such asCSF2,TNF(aliasTNF-alpha) andIL137,38. Also, CRP regulation and haematopoietic development may share pathways potentially through cytokines such as IL1 and TNF-alpha39,40, yet, these results need a detailed examination for ...
Intake of total protein, plant protein and animal protein in relation to blood pressure: a meta-analysis of observational and intervention studies. J Hum Hypertens. 2013;27(9):564-571. doi:10.1038/jhh.2013.16 PubMedGoogle Scholar 7. Rebholz CM, Friedman EE, Powers LJ,...
Liver cells of persons chronically infected with hepatitis B virus (HBV) shed excess viral surface protein into the blood; that is, hepatitis B surface antigen (HBsAg). HBsAg was identified as a 22-nm lipoprotein particle antigen with protective epitopes. To develop a vaccine, plasma was ...
Through examination of more readily accessible blood cells, individuals carrying SNCA triplication or a greater number of Rep1 dinucleotide repeats were shown to have elevated levels of α-synuclein protein levels in peripheral blood mononuclear cells (PBMCs) in addition to increased SNCA mRNA (Fuchs...
The activation of the unfolded protein response (UPR) is closely linked to the pathogenesis of renal injuries. However, the role of XBP1, a crucial regulator of adaptive UPR, remains unclear during the transition from acute kidney injury (AKI) to chronic
et al. C-reactive protein induces human peripheral blood monocytes to synthesize tissue factor. Blood.1993;82:513-520.Google Scholar 41. Harris TB, Ferrucci L, Tracy RP. et al. Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly. Am J Med....
They observed that fluctua- tions in the P/C ratio values based on the time of urine collection were explained by differences in the physical activity of the women during the day, variable blood pressure, emotional state and posture. They empha- sized that for these women, P/C ratio tests...
The aggravated blood phenotypes may be explained by the unrepaired DPCs in transcribed regions. Note that AMeDS patients display additional manifestations, not observed in FA, such as neurological abnormalities and dwarfism, reminiscent of TCR-deficient CS. This suggests that the accumulation of ...
Independent controls to test the mathematical model To experimentally verify the model, we performed some initial controls in vivo. First, we measured the soluble 13C6-lysine pool, through a gas-chromatography MS approach applied on the mouse blood plasma, which should closely reflect the free sol...