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Bacteria appear to be simply organized organisms, but bacterial cells do have different subcellular compartments: the cytoplasm, the cytoplasmic or inner membrane (IM), the cell wall and in the case of gram-negative bacteria, the periplasm and the outer membrane (OM). Proteins are synthesized ...
Membrane proteins in bacteria are cotranslationally inserted into the plasma membrane through the SecYEG translocon. Ribosomes exposing the signal-anchor sequence (SAS) of a membrane protein are targeted to the translocon by the signal recognition partic
This list of proteins was highly enriched for gene ontology pathways related to protein targeting to membranes (Supplementary Data 4). A considerable subset of proteins which associated with EGFR in our prior analysis of the EGFR interactome (84/431) also associated with RanBP6 (Fig. 1f; ...
mTPs function as targeting signals and are necessary and sufficient for targeting of precursor proteins to the organelle (for reviews see Neupert & Herrmann, 2007; Schleiff & Becker, 2011). Membrane proteins usually lack the N-terminal extensions and contain non-cleavable targeting and sorting ...
Protein targeting or protein sorting is the biological mechanism by which proteins are transported to the appropriate destinations in the cell or outside of it. Proteins can be targeted to the inner space of an organelle, different intracellular membranes, plasma membrane, or to exterior of the ...
targeting. It would suggest that during their initial transfer to the host nucleus they acquired signal peptides, rather than transit peptides, consistent with the idea that ES targeting of proteins was present at the earliest stages of primary plastid evolution (Figure1B1). Alternatively, if ...
Targeting of the SUN protein Mps3 to the inner nuclear membrane by the histone variant H2A.Z. Journal of Cell BiologyGardner, J.M. et al. (2011) Targeting of the SUN protein Mps3 to the inner nuclear membrane by the histone variant H2A.Z. ... Gardner,Jennifer,M.,... - 《Journal ...
The members of this family contain an array of multiple beta strands arranged as transmembrane segments in the outer membrane. The mitochondrial targeting signal in these proteins consists of the last beta strands and the loop in between arranged as a hairpin. This signal is recognized by the ...
They were targeted to mitochondria and complemented the temperature-sensitive growth phenotype of deltatom5 yeast cells. The membrane-targeting mechanism of Tom5 appears to be distinct from that for proteins that are dispersed in the outer membrane. 展开 关键词: COS Cells Cell Membrane Mitochondria...