Reviews studies that have used protein synthesis inhibitors to test the hypothesis that memory in part depends on brain protein synthesis. Evidence from learning curves, examination of short-term retention, and posttraining drug injection indicate that initial acquisition is not dependent on such ...
Protein synthesis refers to the biological process whereby amino acids are assembled by peptide bonding into specific polypeptide sequences in accord with genetic blueprints encoded by deoxyribonucleic acid (DNA). From: Encyclopedia of Stress (Second Edition), 2007 About this pageAdd to MendeleySet ale...
We address these questions using coarse-grain molecular dynamics simulations of the synthesis, termination, and post-translational dynamics of a representative set of cytosolicE. coliproteins. We predict that half of proteins exhibit misfolded subpopulations that bypass molecular chaperones, avoid aggregation...
organs and organelles. The progress made in this field is evident in number of research works. However, research on riceprotein phosphorylationis still at its infancy and there are still many unanswered questions. In this review, the general description of protein phosphorylation, including history,...
1c). Protein synthesis is constrained by the synthesis of ribosome and other machineries, such as secretory machinery complexes (Fig. 1c). Each metabolic flux in the model is constrained by the maximal capacity of the associated enzyme, which is a function of turnover rate (kcat) and the ...
protein synthesis, anabolic signaling, gene expression, nitrogen balance ánd resting metabolic rate. None of the measures were different between the 2 protein intakes.Note: Eric pointed out the higher protein group did have higher postprandial protein synthesis levels, but given the non-...
In comparison to phosphorylation, effects of other PTMs, including ubiquitination, SUMOylation, acetylation and methylation, on pRb functions are less understood. Many questions regarding the regulation of pRb functions by these PTMs remain to be addressed, particularly about the cellular contexts in ...
There can be more additional questions added and the framework/checklist can act as a guide to the specific task in hand. While, there are many success stories inde novoprotein design, there are some challenges for the road ahead. Some of the challenges that have been discussed (Kuhlmanet al...
Bacterial protein acetylation: new discoveries unanswered questions. Curr. Genet. 62, 335–341 (2016). Article CAS PubMed Google Scholar Weinert, B. T. et al. Accurate quantification of site-specific acetylation stoichiometry reveals the impact of sirtuin deacetylase CobB on the E. coli ...
which controls the translational efficiency. These two proteins are necessary for attenuation of protein synthesis in response to osmotic stress [50], and the interaction among them was observed in the constructed subnetwork. Several proteins influence nuclear residence of Hog1p, such as the tyrosine ...