In addition, the β-sheet structure is characterized by a negative peak at 217 nm and a positive peak at 195–200 nm. They also calculated the contents of the MBPI secondary structure in different pH conditions. The α-helix structure content was lower at pH 5 (6.32 %) than at pH 3...
Related to Protein secondary structure: alpha helixsecondary structure n. The three-dimensional structure of the polypeptide backbone of a protein (such as alpha helix, beta sheet, and coil patterns), or the sugar-phosphate backbone of a nucleic acid (such as the double helix pattern of DNA)....
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We first define the level of disorder in a protein by its secondary structure content. When dividing the test set into bins, we separate protein sets based on a decreasing coil content and corresponding increasing helix/beta content. 1672 proteins in the test set were divided into five bins ...
the PDB with secondary structures consistent with the diagram 被生成using the Rosetta de novo structure prediction methodology(18),产生了 172 个 backbone-only models thathad the desired topology and secondary structure contentandhad root mean square deviations (RMSDs) from each other of 2 to 3 ...
1、Protein Structure,Content,1,2,3,definition: the spatial arrangement of a portion of a polypeptide only involving atoms of the backbone core,the most common helix of polypeptide found in nature existing in many different proteins,1. structure: core: extending part,2. feature,a tightly packed...
Protein secondary structure prediction is one of the most important and challenging problems in bioinformatics. Machine learning techniques have been applied to solve the problem and have gained substantial success in this research area. However there is still room for improvement toward the theoretical ...
摘要: Far-UV circular dichroism (CD) spectroscopy is a classical method for the study of the secondary structure of polypeptides in solution. It has been the general view that the α-helix content can be...关键词:Amyloid Circular dichroism Protein fold Protein secondary structure β-sheet ...
It accepts as input a circular dichroism spectrum and outputs the estimated secondary structure content (alpha-helix and beta-strand) of the corresponding protein, as well as an estimated measure of error.Background Circular dichroism (CD) spectroscopy is a widely used technique to analyze the ...
Protein structural data has increased exponentially, such that fast and accurate tools are necessary to access structure similarity search. To improve the search speed, several methods have been designed to reduce three-dimensional protein structures to