platelet-rich plasmaOral Lichen Planus (OLP), an autoimmune disorder of unclear pathogenesis affects quality of life of affected individual. Intervention regimens are multiple and still evolving due to its resistance to recover and ability to recur. Platelet rich Plasma (PRP) is a newer, promising...
In terms of cellular component (CC), these proteins were involved in cytoplasmic vesicle lumen, secretory granule lumen, triglyceride-rich plasma lipoprotein particle, and very-low-density lipoprotein particle. Moreover, for the aspect of molecular function (MF), these targets were enriched in ...
Here, we report several pleiotropic compounds that act on the rich-club and are candidates for potential consideration in stroke therapy while focusing on estrogen, the drug with most enriched targets in the network. Scientific Reports | 5:13513 | DOI: 10.1038/srep13513 10 www.nature.com/...
Interventions A diet rich in carbohydrates; a diet rich in protein, about half from plant sources; and a diet rich in unsaturated fat, predominantly monounsaturated fat. Main Outcome Measures Systolic blood pressure and low-density lipoprotein cholesterol. Results Blood pressure, low-density lipoprotein...
Briefly, the glycine (Gly)-rich loop connecting the first two β-strands of the N-lobe helps position ATP for catalysis. All subsequent regions of interest are located in the C-lobe. The catalytic loop contains a critical HRD (His-Arg-Asp) motif involved in phospho-transfer and ...
Ibanez RIR, do Amaral RJFC, Simpson CR, Casey SM, Reis RL, Marques AP, Murphy CM, O’Brien FJ. 3D Printed scaffolds incorporated with platelet-rich plasma show enhanced angiogenic potential while not inducing fibrosis. Adv Funct Mater. 2022;32(10):2109915. ...
(also Znf36L1), is elevated bycAMPin adrenal cells in parallel with StAR mRNA. TIS11b selectively destabilizes the 3.5kb mRNA through AU-rich sequences at the end of the 3′UTR.siRNAsuppression shows that TIS11b surprisingly increasesStAR proteinandcholesterol metabolism. StAR transcription is ...
Effects of a Protein-Rich Diet during Convalescence from Shigellosis on Catch-up Growth, Serum Proteins, and Insulin-Like Growth Factor-I IQBAL KABIR, THOMAS BUTLER, LOUIS E. UNDERWOOD, AND M. MUJIBUR RAHMAN International Cenlre (of'Diarrhea1Disease Research, Bangladesh [I.K., M.M.R.];...
Metalloproteinases are also potential indicators of arterial inflammation, and, by degrading extracellular matrix, may contribute to the fragility of the lipid-rich, atherosclerotic plaque and eventually to its rupture. As previously described for several other metalloproteinases (MMP-1, -3, -12, or ...
The second region (pocket 2) is close to the C terminal of Skp2, formed by a Leu-rich repeat sequence with some residues from the F-box domain (Fig. 9b). Inhibitors bind to one or both of these pockets prevent the formation of Skp2–Skp1 complex. Chan et al.173 identified seven ...