Introduction The Protein Processing Assembly Line Polypeptide Production The Endoplasmic Reticulum: Polypeptide Folding and Modification Overview of the ER Lumen Folding in the ER Glycosylation in the ER Glycosy
待解决 悬赏分:1 - 离问题结束还有 Protein processing in endoplasmic reticulum问题补充:匿名 2013-05-23 12:21:38 内质网蛋白加工 匿名 2013-05-23 12:23:18 蛋白质endoplasmic reticulum加工 匿名 2013-05-23 12:24:58 正在翻译,请等待... 匿名 2013-05-23 12:26:38 正在翻译,请等待......
PPI networks affected by heat stress (ND-H vs. ND-C) included proteins involved in “spliceosome”, “protein processing in endoplasmic reticulum”, “fructose and mannose metabolism” and “carbon fixation in photosynthetic organisms”. Heat stress with drought priming (D-H vs. ND-H) resulted...
16 Also, the additional components were added up to 575, based on collecting relevant components from a comprehensive literature survey and KEGG secretion-related pathways including protein processing in the endoplasmic reticulum (ko04141) and SNARE interactions in vesicular transport (ko04130) (EV1)...
To investigate the level of hepatic ER stress in NAFLD, proteomic analysis of livers from ob/ob mice and the lean controls were performed. KEGG analysis revealed that “protein processing in endoplasmic reticulum” pathway was significantly enriched (Fig. 2A). Further analysis of ER stress pathway...
We now report that gp100 is processed and sorted in a manner distinct from other melanosomal proteins (such as tyrosinase, Tyrp1 and Dct) and is predominantly delivered directly to immature melanosomes following its rapid processing in the endoplasmic reticulum and cis-Golgi. Following its ...
In the ER, proteins are kept in a folding competent state by protein chaperones, immature N- glycans are transferred to the native proteins and undergo initial processing, and intermolecular disulfide bridges are formed. In case of protein overexpression, mutations or aberrant post-translational ...
An exception to this is receptor subunit processing in the endoplasmic reticulum, where misfolded proteins and uncomplexed subunits are recognized and exported for proteasomal degradation through the endoplasmic reticulum-associated degradation pathway (MacGurn et al, 2012). This process is dependent on ...
Metabolic diseases often share common traits, including accumulation of unfolded proteins in the endoplasmic reticulum (ER). Upon ER stress, the unfolded protein response (UPR) is activated to limit cellular damage which weakens with age. Here, we show thatCaenorhabditis elegansfed a bacterial diet ...
Here we report endoplasmic reticulum-associated degradation (ERAD) as a protein quality checkpoint that controls the haematopoietic stem cell (HSC)–niche interaction and determines the fate of HSCs. The SEL1L–HRD1 complex, the most conserved branch of ERAD4, is highly expressed in HSCs. ...