Proteins are composed of smaller building blocks, which are called "domains" or "modules". These building blocks are distinct regions in three-dimensional (3D) structure resulting in protein architectures assembled from modular segments that have evolved independently [3]. The modular nature of prote...
The droplet is composed of 1,503 hexane molecules and was formed with 63,898 water molecules through 2 ns of equilibration and 40 ns of production simulation. The combined system was equilibrated for 2 ns and then run at production setpoints for 100 ns. All simulations followed the...
What type of macro-molecule is frequently an enzyme? a. Carbohydrate b. Nucleic acid c. Protein d. Lipid DNA is a(n): A) lipid B) protein C) carbohydrate D) polymer The building blocks of proteins are: A. fatty acids B. amino acids C. nucleotides D. car...
One of the wonders of nature is that the complexity and diversity of life can be contained in a molecule with a relatively simple structure.Deoxyribonucleic acid,commonly calledDNA,exists mainly in the nucleus and mitochondria of each cell in an organism. It consists of two long strands linked ...
The virus is composed of 60 peripentonal hexons at the bases of the fibers at the fivefold vertices, and groups of 9 hexons, one on each triangular face of the icosahedron. (B) Cryoeletron microscopic reconstruction of an adenovirus virion, viewed down the threefold axis. (C) Space-...
The structure of individual domains and small proteins is defined by the organization of secondary structure and super-secondary structures, also called motifs. Motifs are defined by the composition and organization of α-helices, β-structures, and unstructured loops and often comprise repeating units...
In addition, a large-scale protein dynamics dataset is built for the training and validation of RMSF-net, in which 335 cryo-EM structure entries with fitted PDB models are selected and the corresponding MD simulations are performed. Comprehensive experimental results demonstrate the efficiency and ...
The assembly of proteins, nature’s most powerful and versatile building blocks, into rationally organized arrays is of substantial interest for enabling protein-containing materials and their cell-free functionality1,2,3,4. Establishing approaches for creating protein-based well-ordered structures has ...
Protein fibrils are expected to have applications as functional nanomaterials because of their sophisticated structures; however, nanoscale ordering of the functional units of protein fibrils remains challenging. Here we design a series of self-polymeriz
Design of multi-scale protein complexes by hierarchical building block fusion Introduction The assembly of proteins, nature’s most powerful and versatile building blocks, into rationally organized arrays is of substantial interest for enabling protein-containing materials and their cell-free functionality1...