Protein profiling of urine samples can be used to detect and diagnose transitional-cell carcinoma of the bladder with high sensitivity and specificity, according to a recent study by Liu et al.doi:10.1038/ncpuro0172NoneNature Clinical Practice Urology...
Detection of urine neural thread protein for diagnosis of Alzheimer disease and its clinical significance 来自 ResearchGate 喜欢 0 阅读量: 35 作者:R Wang,ZJ Ji,SL Sheng,JA Zhu,JY Zhang 摘要: Background: Whether the excessive production of beta-amyloid (β-amyloid, Aβ) in the brain of D-...
Urinary protein/creatinine ratio allows veterinary clinicians to quantify proteinuria, i.e., the amount of protein that is lost in urine. This ratio is commonly performed in daily practice for several medical reasons, namely the diagnosis and the monitoring of feline chronic kidney disease. This st...
SRM have been used for theanalysis of proteinsand peptides in body fluids such as blood plasma/serum[154–157]or urine[158,159]. It has been successfully applied to the analysis of Hb variants relevant in hemoglobinopathies[154,155]. Moat et al. developed a protocol for new-born blood ...
Urine creatinine concentration influences the prognostic value of proteinuria for MACE prediction from the findings of the KNOW-CKD study Article Open access 23 September 2022 Population characteristics and diagnosis rate of chronic kidney disease by eGFR and proteinuria in Japanese clinical practice: ...
and urine which fits a criterion to be a strong biomarker candidate. Clinical detection of PDI levels in serum could reflect PDI expression in cancer patients, thus pointing to a potential diagnostic/prognostic significance. PDIA1 has been used as a serum marker for the diagnosis of colorectal ca...
Protein electrophoresis is used to identify and measure the presence of abnormal proteins, the absence of normal proteins, and/or to detect various protein electrophoresis patterns associated with certain conditions, as found in blood, urine or other body fluids. The information from protein electrophor...
The AA sequence of a protein determines the tertiary structure which in turn determines its chemical, biological, and physical function, that is, protein function is derived from structure, and the structure is derived from the sequence, linking the genetic code of protein expression to its ...
Dyslipidemia is a major risk factor for cardiovascular disease, and diabetes impacts the lipid metabolism through multiple pathways. In addition to the standard lipid measurements, apolipoprotein concentrations provide added awareness of the burden of ci
In clinical practice, albuminuria can be assessed using the urinary albumin-to-creatinine ratio (UACR) obtained from a spot urine sample. UACR is widely recommended as a marker to quantify albuminuria for DKD diagnosis and the risk assessment of diabetes-related adverse outcomes8,9. However, ...