A lysosomal disease (storage disease) caused by mutation in the gene encoding the beta subunit of hexosaminidase (EC 3.2.1.52). GM2 gangliosides accumulate, particularly in neurons, leading to progressive neurodegeneration. Clinically indistinguishable from Tay-Sachs disease. ...
Cells were either treated with 100 nM of the protein synthesis inhibitor anisomycin for 25 min or were left untreated and fixed in 3.7% formaldehyde +2 μg/ml Hoechst dye, and fluorescent images were collected on the ArrayScan 3.1 (Fig. 3). Consistent with the fluorescent images in Fig. 2...
How to take 100 gm of protein everyday. Please help. My weight is 76.non vegetarian as well. Please give food suggestions. Asked for Female, 30 Years 67 Views Ms. Hetal Mehta Dietitian/Nutritionist | Mumbai Your protein intake should not be more than 0.8g/kg body weight; else it ...
Liu MY, Xydakis AM, Hoogeveen RC, Jones PH, Smith EO, Nelson KW, et al. Multiplexed analysis of biomarkers related to obesity and the metabolic syndrome in human plasma, using the Luminex-100 system. Clin Chem 2005; 51:1102–9.10.1373/clinchem.2004.047084Search in Google Scholar ...
Fig. 1: Protein half-life distributions for each tissue class in this resource. Histograms are output by ApplE Turnover. Source data are provided with this paper; raw mass spectrometry data are available as described in the “Data Availability” section. Full size image The data used to calcul...
Although protein phosphorylation is an important post-translational modification affecting protein function and metabolism, dynamic changes in this process during ontogenesis remain unexplored in woody angiosperms. Methods Phosphorylated proteins from leaves of three apple seedlings at juvenile, adult vegetative ...
Molecular cloning and expression analysis of a Zinc finger protein gene in apple. CAO Qin-fen,Massato WANG,MENG Yu-ping,et al. Acta Botanica Sinica . 2004Molecular cloning and expression analysis of a zinc finger protein gene in apple. Cao Q F,Wada M,Meng Y P,et al. Acta Botanica ...
It is often the case that mammalian genes are alternatively spliced; the resulting alternate transcripts often encode protein isoforms that differ in amino acid sequences. Changes among the protein isoforms can alter the cellular properties of proteins. The effect can range from a subtle modulation ...
Single Stranded DNA Binding Proteins are proteins that play crucial roles in DNA replication, recombination, and repair by binding to single-stranded DNA with high affinity, regardless of the DNA sequence. They are present in all life forms and utilize a unique protein fold for DNA binding. ...
Wound models that perturb the skin barrier can be used to assess the functional status of the immune system, and provide insight into aspects of immune function that other in vitro and in vivo models do not fully capture, such as innate immune and proinflammatory responses and tissue remodeling...