Protein functions in the cell, such as enzymatic activity, signaling, and transport, are driven by conformational changes between multiple states1,2,3. To understand biological processes at the molecular level, we therefore require a precise description of protein dynamics1. Pump-probe time-resolved ...
1 Introduction Protein tyrosine kinases (PTKs) are kinases that catalyze the transfer of ɣ-phosphate from ATP to protein tyrosine residues [1]. They can also catalyze the phosphorylation of various substrate protein tyrosine residues, which play an essential role in cell growth, differentiat...
L Burger,E Van Nimwegen - 《Molecular Systems Biology》 被引量: 126发表: 2014年 An efficient method for creation and functional analysis of libraries of hybrid type I polyketide synthases. Bacterial type I polyketide synthases (PKSs) generate a structurally diverse group of natural products with ...
Legumes and oilseeds have become the major plant protein sources that generate nonanimal-derived counterparts to those of dairy (eg, milk, cheese, ice cream, yogurt-like desserts), and meat (burger-, frankfurter-, cutlet-like products). When considered as a nutrient, proteins of animal ...
Protein-protein interactions (PPIs) play an essential role in cellular regulatory processes. Despite, in-depth studies to uncover the mystery of PPI-mediated regulations are still lacking. Here, an integrative interactome network (MePPI-Ux) was obtained
Proteins are molecular machines and to understand how they work, we need to understand how they move. New pump-probe time-resolved X-ray diffraction methods open up ways to initiate and observe protein motions with atomistic detail in crystals on biologi
Protein oxidation in emulsified cooked burger patties with added fruit extracts: Influence on colour and texture deterioration during chill storage The influence of protein oxidation, as measured by the dinitrophenylhydrazine (DNPH) method, on colour and texture changes during chill storage (2 掳C, ...
Burger L, van Nimwegen E (2010) Disentangling direct from indirect co-evolution of residues in protein alignments. PLoS Comput Biol 6:1000633. https://doi.org/10.1371/journal.pcbi.1000633 Article CAS Google Scholar Chen XW, Liu M (2005) Prediction of protein-protein interactions using random ...
209and Burger (in sponge cells)210at the end of the 1980s, systematic studies for their quantification with model systems appeared in the literature only ten years later.24,64,211The existence of this interaction is nowadays generally accepted, but clarification of the mechanisms, and further ...
Koenig and Burgermeister (1986) discuss the application of various immunoblotting techniques and consider the problem of unexplained or false-positive reactions that sometimes occur. These reactions may be due to non-specific binding of immunoglobulins to coat proteins of certain plant viruses (Dietz...