To determine whether the identified sex-specific causal proteins show sex-specific genetic risk, we asked whether the genetic interaction with sex in the corresponding GWAS was nominally significant for the considered trait for the sites that were most significantly associated with the trait at the lo...
81 Higher protein consumption has been associated with a dose-responsive lower risk of incident frailty in older women.82 Incorporating more protein into the diet is thus a rational strategy for frailty prevention. Hip fracture Older adults (average age 84) with hip or leg fracture who entered ...
SARS-CoV-2 is one of the worst examples, which have infected over 400 million individual and killed 5.7 million worldwide.144,145 TPD could represent a novel antiviral therapeutic approach. One of the first successful examples is used for the degradation of hepatitis C virus (HCV) NS3/4A ...
Moreover, reported functional limitations are higher in women (12), and improving nutritional status for women, especially earlier in life, could be helpful for preserving functional status during aging (13). Social and biological health-related factors may similarly underpin the higher functional ...
Comparison of high protein and high fiber weight-loss diets in women with risk factors for the metabolic syndrome: a randomized trial Studies have suggested that moderately high protein diets may be more appropriate than conventional low-fat high carbohydrate diets for individuals at risk... LAT Mo...
The eligibility of breast cancer patients for human epidermal growth factor receptor 2 (HER2)-directed therapies is determined by the HER2 gene amplification and/or HER2 protein overexpression status of the breast tumor as determined by in situ hybridiza
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Given a HPV-11 prevalence rate of 5–12% in normal women [6–8], a serious recent concern is the impact of increasing human immunodeficiency virus (HIV) infection rates, and the associated immunosuppression of HIV-positive individuals, on HPV-6 or 11 coinfections. HPV-associated disease is ...
A recent study reported that soy nuts, which are high in soy protein, reduced BP inpostmenopausal womenfollowing a Therapeutic Lifestyle Changes (TLC) diet for 8 weeks (Welty et al., 2007). SBP and DBP decreased by 9.9 and 6.8%, respectively, in hypertensive women following the soy-nut ...
Ahren, B. Islet G protein-coupled receptors as potential targets for treatment of type 2 diabetes. Nature Rev. Drug. Discov. 8, 369–385 (2009). This is an excellent review on the role of GPCRs in the regulation of pancreatic β -cells and their established or potential roles as targets...