To preserve the TG mouse lines and maintain a significant number of samples for our experiments, female mice of each strain followed continuous breeding, and male mice were utilized for all experiments. We maintained a grouping of four mice per cage housed in a temperature- and humidity-...
For the bite experiment in Figure S1, 4-week-old female C57BL/6JRj mice were injected intraperitoneally with 100 μg/mouse of the hmAb 311. After 24 h, mice were anesthetized with a mixture of ketamine (50 mg/kg body weight; IMALGENE1000, Boehringer Ingelheim) and xylazine (5 mg/kg ...