To determine whether the identified sex-specific causal proteins show sex-specific genetic risk, we asked whether the genetic interaction with sex in the corresponding GWAS was nominally significant for the considered trait for the sites that were most significantly associated with the trait at the lo...
1 A–H illustrates Bland–Altman plots of mean differences and limits of agreement between actual or corrected bodyweight and FFM, stratified for BMI categories for men and female separately. Clinically relevant differences were found in protein requirement between actual bodyweight and FFM in most ...
In recent years, some PPIs modulators have entered clinical studies, some of which been approved for marketing, indicating that the modulators targeting PPIs have broad prospects. Here, we summarize the recent advances in PPIs modulators, including small molecules, peptides, and antibodies, hoping ...
Meaning The recommended dietary allowance for protein is sufficient to maintain lean body mass; protein intake exceeding the recommended dietary allowance does not increase lean body mass in functionally limited older men who are eating less than the recommended dietary allowance. Abstract Importance The...
Prof. Levine is best known for discovering the first mammalian autophagy gene BECN1108. Moreover, she noticed that the BECN1 gene was often deleted monoallelically in tumor cells, indicating a link between autophagy and tumor suppression109. This discovery has been standing as a true landmark ...
Varadi, Met al. AlphaFold Protein Structure Database in 2024: providing structure coverage for over 214 million protein sequences.Nucleic Acids Research(2024). If you use data from AlphaMissense in your work, please cite the following paper: ...
Steve, Recently you recommended me to try the “Fat loss for men diet with HIIT training” and it seems to be a good workout but ive always wondered about all the routines seem to have upperbody and lower body mixed in on the same day.I always have been taught as well as heard,that...
The average protein requirement is based on nitrogen loss by urine, stool, hair, nails, and transpiration (50) plus the extra protein needed for growth (51). The nitrogen amount is calculated and converted to protein with the factor 6.25. The protein requirements for individuals following lacto...
et al. Understanding the nanoparticle–protein corona using methods to quantify exchange rates and affinities of proteins for nanoparticles. Proc. Natl Acad. Sci. USA 104, 2050–2055 (2007). Article CAS Google Scholar Bangham, A. D., Pethica, B. A. & Seaman, G. V. The charged groups...
See E classification for enzymes. EC50 Effective concentration; concentration at which the substance concerned produces a specified effect in 50% of the organisms treated or 50% of the maximal effect. eccrine Type of gland in which the secretory product is excreted from the cells. ecdysis Moulting...