Overview WoLF PSORT is an extension of the PSORT II program for protein subcellular localization prediction, which is based on the PSORT principle. WoLF PSORT converts a protein's amino acid sequences into numerical localization features; based on sorting signals, amino acid composition and functiona...
This review divides protein domain prediction methods into two categories, namely sequence-based and structure-based. These methods are introduced in detail, and their advantages and limitations are compared. Furthermore, this review also provides a comprehensive overview of popular online protein domain...
Predicting protein structures from amino acid sequences used to be difficult and error prone. This changed in 2021 when AlphaFold2 reported near-experimental accuracy for most single-domain proteins. We look back on this breakthrough, discuss its effect on the field, and highlight AlphaFold3, a...
a number of protein domain identification approaches have been developed, and a variety of protein domain databases have also been constructed. This review divides protein domain prediction methods into two categories, namely sequence-based and structure-based. These methods are introduced in detail, an...
In addition to commonly used baselines in the automatic function prediction tasks, we also considered machine learning methods that had an open-source implementation that we could train from scratch on our dataset. BLAST—basic local alignment search tool ...
outperforms the current state-of-the-art flexibility prediction tool PROFbval for a binary classification problem and provides more precise flexibility prediction in three and five classes. MEDUSA is freely available as a web-server providing a clear visualization of the prediction results. Analysis ...
(e) Percentage of fully dark UniRef50 clusters with proteins annotated as a domain of unknown function (DUF) in each set a-e. Extended Data Fig. 2 Structural conservation and structure-based function prediction of TumE. Structural superposition of five randomly selected members of component 159 ...
proteinstructure-prediction3d-structureprotein-complexes UpdatedMar 2, 2025 Jupyter Notebook A collection of research papers for AI-based protein design awesomeprotein-structureartificial-intelligenceproteinawesome-list UpdatedMay 13, 2024 Ribbon diagrams of proteins in #golang. ...
each protein in one PPI has orthologs in the second PPI37. While a useful prediction tool, detecting an interolog in a new system requires established reference PPIs from other systems. This constraint by available data would result in a very limited number of predictions when analyzing interactio...
Neutrophil elastase binds at the central domain of extracellular Toll-like receptor 4: AI prediction, docking, and validation in disease model Azeem Ali Leena Gaba Prem Prakash ResearchOpen Access18 Mar 2025 Scientific Reports Volume: 15, P: 9282 All Research & Reviews News and Comment Cele...