S should be followed by D for deletion (SD_), if amino acids are missing compared to the canonical protein record described by the protein accession and sequence version number. If, say, the unspliced protein species consists of 100 amino acids and the spliced species is missing the amino ...
The Ideal Protein diet is a low-carbohydrate, low-calorie, high-protein diet that aims to aid in weight loss by providing the body with the right amount and kind of protein while also stabilizing blood sugar. It consists of four phases. During the first three phases, participants eat at le...
Many proteins that bind to deoxyribonucleic acid (DNA) and regulate gene expression incorporate a zinc finger motif. As the name implies, this motif binds the zinc ion using combinations of the amino acids cysteine and histidine. One type of zinc finger motif consists of a single α helix ...
The 55S mammalian mitochondrial ribosome consists of a small (28S) and a large subunit (39S). The small subunit (SSU) contains a 12S rRNA and 30 proteins while the large subunit contains of a16S rRNAand 48 proteins[24,25]. Both the 12S and the 16S rRNAs are encoded by themitoch...
The core protein consists of 153aa with 24 serine-glycine repeats between amino acids 89 and 137, hence the name. The serine-glycine repeats are the linkage sites for around 15 glycosaminoglycan chains that are either heparin or highly sulphated chondroitin sulphate. These negatively charged chains...
The designed protein consists of 780 amino acids with a molecular weight of 85247.31 daltons. The results of the interaction of the vaccine candidate with TLR2 and TLR4 of the immune system also showed that there are strong interactions between the vaccine candidate protein with TLR2 (-890.7 kca...
The MAP kinase cascade consists of three component kinases (MAP kinase, MAP kinase kinase, and MAP kinase kinase kinase). Activation of Ras recruits Raf-1 Ser/Thr kinase (MAP kinase kinase kinase) to the plasma membrane, where Raf-1 is phosphorylated and activated by an unidentified kinase(s...
Vpu produces a protein of 16 kDa that consists of 82 AA.Viral proteinU is a type-1 integral membranephosphoproteinunique to HIV. The genomic location ofvpuis from nucleotide 5608–5856, and it consists of 248 nucleotides. Vpu enhances pathogenesisin vivo,even though it is not an essential pr...
Note that the β-sheet topology that consists of parallel-aligned β-strands with a 3142 strand order (numbered 8 in the figure) forms a knot; this topology has not been observed in nature and has long been considered to be impossible to exist18,19,20,21. However, we selected this ...
Despite this sustained interest over many years, so far there is no clear theoretical framework1,2,3,4, and essentially formulation consists of trying out previously successful ideas5. The aim of this work is to establish some of the fundamental science, in particular the relative importance of...