we learn multiple, but finitely many, such models and generate predictions of functions as ‘approximate’ semantic entailment where we test for truth in each of the generated world models. Using this form of approximate semantic entailment, we show that the axioms in the extended version of GO ...
These results demonstrate the ability of DMFold-Multimer to model large protein complexes, which has been a long-term challenge for traditional quaternary structure modeling approaches23. In Fig. 6c and Supplementary Table 9, we also list a comparison of DMFold-Multimer (named Zheng) with 86 ...
For B. mori silk fibers, the effect of pre-extension on the mechanical properties was tested, using a short-term stress-relaxation process. Preliminary extension of >3% shifted the yield point from ~5% to 6–8%, while the stress at rupture also increased to around 10–20% after preliminary...
In short-term studies,12-14 protein intakes exceeding the RDA were reported to promote apparent nitrogen retention and stimulate leucine kinetics. However, studies15-21 of older adults fed protein greater than the RDA have shown inconsistent improvements in LBM and physical function. Many studies ...
(1) Inclusion bodies within cells, often of virus particles, although this term is more common in the older literature. (2) Infectious extracellular form of Chlamydia, consisting of electron-dense nuclear material and a few ribosomes surrounded by a rigid trilaminar wall. Once taken up by cell...
Similarly, a retrospective study revealed a higher proportion of B blood type patients among those with long-term diabetes before PC diagnosis than that among PC patients without diabetes at diagnosis [70], which also implied the intricate interaction between ABO blood type, diabetes mellitus, and ...
Osborne JD, Lin S, Zhu L, Kibbe WA: Mining biomedical data using MetaMap Transfer (MMtx) and the Unified Medical Language System (UMLS). Methods Mol Biol. 2007, 408: 153-169. 10.1007/978-1-59745-547-3_9. Article PubMed CAS Google Scholar Salton G, Buckley C: Term-weighting approac...
The term neural tube defect is used to describe various degrees of failure of formation of the central nervous system (brain and spinal cord) and its coverings. The neural crest is the basic embryological structure which folds upon itself to form the brain and spinal cord. This folding process...
DNA–protein crosslinks (DPCs) arise from enzymatic intermediates, metabolism or chemicals like chemotherapeutics. DPCs are highly cytotoxic as they impede DNA-based processes such as replication, which is counteracted through proteolysis-mediated DPC re
Apart from the functional term “protein tetramerization” associated with the formation of the protein complex itself (6.19-fold enrichment;P = 3 × 10−23), the most significantly enriched GO terms are all related to metabolic processes. For example, more than 60% of the dihedral ...