Variation in the gene encoding dysbindin-1 (i.e., dystrobrevin-binding protein 1: DTNBP1) has frequently been associated with schizophrenia. Several studies have also found that dysbindin-1 gene and protein expression are altered in two affected brain ar
Most patients with active CD have elevated CRP, although there are studies with contradictory results when correlating clinical activity and their values; we also found that up to 10% of patients with CD and clinical criteria of activity may present persistently normal CRP values.4,5 Its role ...
2c. Horizontal line represents the mean of each group. c) Editing rate of the UAG stop codon in the best performing sensor in each gene group from b. One-tailed unpaired t-test’s carried between the ontarget siRNA group and the non-target siRNA group. (*, p<0.05. **, p<0.01. ...
359). The means of the effect size estimates are presented with 95% CIs and were converted to kg m−2. Extended data can be found in Supplementary Tables1and4.b, Variant-level results from the BOLT-LMM algorithm using
scores: average predicted local distance difference test (pLDDT) of sequence rmsd: motifRMSD between predicted motif coordinates and crystal motif coordinates model: model type used for generations Docker The Docker image for EvoDiff is hosted on DockerHub athttps://hub.docker.com/r/cford38/evo...
(8). We used both ordinary test statistics (analyzing each protein separately) and the moderated test statistics using LIMMA. We recorded false positives and false negatives for a variety of significance thresholds, and averaged the results over 1000 iterations. Since the power to detect ...
Pediatric Rheumatology Juvenile arthritis disease activity score (JADAS) based on C-reactive protein predicts DMARD treatment in juvenile idiopathic arthritis in a Nordic multicenter cohort Ellen Nordal 5 Marek Zak 0 Lillemor Berntson 7 Kristiina Aalto 6 Suvi Peltonieli 3 Susan Nielsen 0 Troels ...
In particular, these interactions are less often supported by yeast two-hybrid, and more often by more complex experiments such as biochemical activity assays. Our analysis showed that high-throughput and literature-curated interactome datasets are more correlated than commonly assumed, but that this ...
b MAGMA gene-property analysis results are shown for average expression of 30 general tissue types, the red line indicates the Bonferroni threshold (p = 1.67 × 10−3). c MAGMA gene-set analysis plot of the Bonferroni significant (p < 3.23 × 10−6) gene-sets. ...
Elevated levels of circulating high-sensitivity C-reactive protein (hs-CRP) have been observed in depression, with the body mass index (BMI) being a major mediator of this association. However, the sex difference in the association between hs-CRP and depression remains unclear. This study aimed...