(Boggs, 2006). MBP and PLP are the characteristic marker proteins ofoligodendrocytes, their localizations also show diversity, such as MBP localizes in plasma membrane, while PLP presents in intracellular (Skorupa et al., 2001). MBP, the myelin essential structural protein, has been called the...
Two arbitrary protein embeddings are combined by concatenation operations, and a Multi-Layer Perceptron (MLP) is then applied as a classifier for prediction. Moreover, we also consider graph attention (GAT) and arbitrarily deploy two of the three GNN layers (i.e., GCN, GIN and GAT) on ...
Relative quantitation of miR-26a-regulated proteins that were involved in the p53 signaling pathway using sequential window acquisition of all theoretical mass spectra (SWATH-MS), parallel reaction monitoring (PRM), and western blot. The SWATH-MS and PRM results are presented as ratios (mean ±...
metal,metallic element- any of several chemical elements that are usually shiny solids that conduct heat or electricity and can be formed into sheets etc. spelter- impure zinc containing about three percent lead and other impurities (especially in the form of ingots) ...
Volume and composition of cellular water, also known as internal milieu, are critica... Kwon,M H. - 《American Journal of Physiology Cell Physiology》 被引量: 99发表: 2008年 The in Vivo and in Vitro Aggregation Properties of Globular Proteins Correlate With Their Conformational Stability: The ...
Localization and function The names, ligands and functions of the 15 hormone recep- tors in family B1 are summarized in Table 1. As mentioned above, nine of the ligands are structurally related and three of the receptors respond selectively to different ligands that are all synthesized by post...
the interactions between molecules play a critical role in binding affinity. When modeling a protein-ligand complex as a graph, protein atoms and ligand atoms are connected based on distance, but short distance does not necessarily mean similar features. This leads to the graph not having strict ...
which terminally differentiate into secretory (enteroendocrine cells, Paneth cells, and goblet cells) and absorptive (enterocytes) cell lineages18. In addition, there is another stem cell pool residing at position +4 from the crypt base, and these cells are also known as reserve ISCs marked by ...
Although there are emerging tools for scalable homology search on structural databases27, as well as for embedding proteins for either search or alignment28,29 (Table 1), tools that perform explicit structural similarity search and alignment on large protein sequence databases are also needed. Table...
PDIA1 (also known as PDI) and ERp57 are two most studied PDIs. PDIA1 is the most abundant oxidoreductase accounting for almost 2% of all ER proteins [58], and uniquely exhibits both oxidoreductase and chaperone activities [59]. ERp57 specifically promotes the folding of glycoproteins via the...