PstS1 protein or fragments thereof are highly immunogenic protein antigens for vaccination and immunotherapy of cancer in humans and animals. A wild-type or a recombinant mycobacterial PstS1 protein are used for the preparation of a vaccine or therapeutical composition for the treatment of cancer,...
A protein C antigen test is normally ordered either along with or as a follow-up to aProtein C activity test. Together, the results from these tests can help to determine if a person's deficiency is due to the quantity or the function of their protein C. AProtein C Deficiency Panelwhich...
A novel centrosome protein, TCC52, was identified as a cancer-testis (CT) antigen. The TCC52 gene was tissue-restricted in normal tissues but highly expressed in lung cancer tissues and some cancer cell lines. Immunoglobulin G antibody specific to TCC52 was detected in serum samples from patie...
C.E. Thirkill et al., "The Cancer Connection: The Retinal CAR Antigen is Expressed in Small Cell Carcinoma of the Lung," Invest. Ophthal. Vis. Sci. 33(4): 847 (1992). G.J. Schmidt et al., "A-Protein Catalyzes Rapid Inositol Metabolism in the Bovine Rod Outer Segment," (A.R....
Depending on the functional test results, the amount of protein C antigen and free, or sometimes total, protein S antigen may be measured to determine if decrease in activity is due to decreased production or abnormal function and to help classify the type of deficiency. If the protein S or...
Blood test offers an attractive alternative for MBC management by analyzing circulating tumor-related biomarkers in a minimally invasive and repeatable manner6. Carcinoma antigen 15-3 (CA 15-3) is the most widely used plasma/serum biomarker in monitoring MBC, yet its response parallels disease respo...
High grade serous ovarian carcinoma (HGSOC) accounts for ~ 70% of ovarian cancer cases. Non-invasive, highly specific blood-based tests for pre-symptomatic screening in women are crucial to reducing the mortality associated with this disease. Since
Deciphering the role of plasma proteins in pancreatic cancer (PC) susceptibility can aid in identifying novel targets for diagnosis and treatment. We examined the relationship between genetically determined levels of plasma proteins and PC through a syst
A self-enhanced ECL-RET immunosensor for the detection of CA19–9 antigen based on Ru (bpy) 2 (phen-NH2) 2+-Amine-rich nitrogen-doped carbon nanodots as probe and graphene oxide grafted hyperbranched aromatic polyamide as platform. Anal Chim Acta. 2020;1132:55–65. Article CAS Google ...
Cytoskeleton-associated protein 2-like (CKAP2L), a cell cycle-related protein, is correlated to tumor progression in some tumors. But there were no pan-cancer studies on CKAP2L, and its role in cancer immunotherapy is also unclear. The expression levels,