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The three-dimensional (3D) structure of a protein is intrinsically linked with its molecular function. Experimental structure determination is an expensive and time-consuming process, and homology-based computational prediction loses its power for proteins without close homologues8. Notwithstanding, deep le...
After six months, researchers found the high protein group had significantly improved their muscle function -- almost twice as much as the control group. "They were able to walk faster, had improved balance, and were also able to get up out of a chair faster than the control group." ...
Many dataset is in the form of high throughput screening data, which have only drug and its activity score. It can be formulated as a drug property prediction task. We also provide a repurpose function to predict over large space of drugs. ...
Secondly, the brain-specific angiogenesis inhibitors 1, 2 and 3 (BAI1, BAI2, BAI3), a group of proteins that have been implicated in the vascular- ization of glioblastomas. Thirdly, the protein encoded by the Drosophila gene flamingo, also known as starry night, and its orthologs in ...
Itsproteincontent of up to 60 %, and is rich in amino acids. 其蛋白质含量可达60%, 并含有丰富的氨基酸. 期刊摘选 Sequence of acidic bovine neuropeptide 1 ( ABNP 1 ) was carried out on PE ABI 491 A ModelProteinSequencer. 用PE?ABI491A型蛋白测序仪对酸性牛神经肽1 ( ABNP?1 ) 进行了测序...
Chemical synapses are asymmetric intercellular junctions through which neurons send nerve impulses to communicate with other neurons or excitable cells. The appropriate formation of synapses, both spatially and temporally, is essential for brain function and depends on the intercellular protein-protein intera...
A Survey of Deep Learning Methods in Protein Bioinformatics and its Impact on Protein Design Weihang Dai arXiv:2501.01477 The Promise of Protein Design: A Q&A with Nobel Laureate David Baker David Baker and Fay Lin GEN Biotechnology (2025) Protein design and structure solution for drug discovery ...
Chemical probes are selective small-molecule modulators, usually inhibitors, of their target protein’s function, that can be used in cell or even animal studies to interrogate the functions of their target proteins. Cheryl Arrowsmith, the leader of a ne