Interventions using dietary protein in obesity may be useful, especially during energy restriction but also in sarcopenic obesity. Furthermore, metabolic profiles that encompass alterations in certain amino acids can provide valuable insights into the metabolic condition of patients with obesity, ...
b and c Cellular localization of GFP-PER1 and endogenous TJP1 b and statistical analysis of the results c in primary hepatocytes cultured in a collagen sandwich configuration in response to treatment with amino acids and/or Torin1. Mouse primary hepatocytes incubated with amino acid-free RPMI1640...
Peptides and proteins are widely used to treat a range of medical conditions; however, they often have to be injected and their effects are short-lived. These shortcomings of the native structure can be addressed by molecular engineering, but this is a c
Soyprotein is an edible protein (after heat processing) that is produced within soybeans. When removed from soybeans via crushing or extrusion involving adequate heat treatment,soy proteinis (historical average) composed of the followingamino acids: 2.5% cysteine, 3.4%histidine, 5.2%isoleucine, 8.2...
This difference was deemed clinically meaningful because it was shown to be associated with improvements in muscle strength and physical function in other functionally limited populations.43 We assumed that the SD of change in LBM in the treatment arms would range between 2.5 and 4.0 kg. This ...
In the fed state, however, most researchers now agree that there is an impairment of the muscle protein anabolic response to meal intake in older adults,46, 49, 50 although some studies found no difference between older and younger adults, especially when high amounts of amino acids or ...
Whey protein: Whey protein, derived from milk, is renowned for its high biological value and rapid absorption rate, making it an ideal post-workout supplement. Casein: Casein, also a milk derivative, is characterized by its slow digestion rate, providing a sustained release of amino acids, thu...
(I) and use thereof forthe treatment and/or prevention of metabolic disorders mediated by insulin resistance or pyperglycemia, comprising diabetestype I and/or II, inadequate glucose tolerance, insulin resistance,hyperlipidemia, hypertriglyceridemia, hypercholesterolemia, obesity, polycystic ovary syndrome (...
Whether the relationship between type 2 diabetes mellitus (T2DM) and osteoarthritis (OA) can be solely attributed to the shared risk factors, such as obesity, remains controversial. Several studies have revealed the critical role of abnormal glycosylatio
obesity. The role of genetic variation in determining protein level variation has not been assessed in obesity. To address this, we design a large-scale protein quantitative trait locus (pQTL) analysis based on a set of 1129 proteins from 494 obese subjects before and after a weight loss ...