样本: Signal peptide, CUB and EGF-like domain-containing protein 1 ELISA Kit 检测方法: 详见说明书 应用: ELISA 检测限: 0.156-10 ng/mL 货号: BK-F99092 是否进口: 是 ELISA试剂盒实验原理: ELISA是以免疫学反应为基础,将抗原、牽9体的特异性反应与酶对底物的高效催化作用相结合起来的一种敏感...
Beyond signal peptide fragments, multiple substrates of human SPP have been reported45,46. It should not escape our attention that some cleaved products from BID1-mediated degradation of SP frag- ments may have novel functions in nodule cells, and BID1 may have a broader spectrum of substrates...
signal peptide-binding drug as a selective inhibitor of co-translational protein translocation:信号肽结合药物作为一种选择性抑制剂的共转化蛋白易位.pdf,Signal Peptide-Binding Drug as a Selective Inhibitor of Co-Translational Protein Translocation 1,2,3 4
In summary, a nodule-specific SPP is necessary for ER-symbiosome proximal association, host protein secretion, and symbiosome differentiation.#During nitrogen fixing symbiosis, rhizobia enter legume nodule cells to form the symbiosome. Here the authors report that a nodule-specific signal peptide ...
Signal peptides (SPs) are short amino acid sequences that control protein secretion and translocation in all living organisms. SPs can be predicted from sequence data, but existing algorithms are unable to detect all known types of SPs. We introduce SignalP 6.0, a machine learning model that ...
N-terminal cleavable signal peptides (SP) direct nascent soluble and type-I transmembrane (TM) polypeptides into the endoplasmic reticulum (ER) and the secretory pathway1,2,3. SP sequences vary in composition and length, but all have polar regions flanking a hydrophobic core which inserts into...
3. Preprotein targeting to SecA is thought to involve signal peptides4and chaperones like SecB5,6. Here we show that signal peptides have a new role beyond targeting: they are essential allosteric activators of the translocase. On docking on their binding groove on SecA, signal peptides ...
Signal peptides (SPs) are short amino acid sequences that control protein secretion and translocation in all living organisms. As experimental characterization of SPs is costly, prediction algorithms are applied to predict them from sequence data. However, existing methods are unable to detect all kn...
To make sense of the exploding diversity of machine learning approaches, we introduce a unifying framework that classifies models on the basis of their use of three core data modalities: sequences, structures and functional labels. We discuss the new capabilities and outstanding challenges for the ...
The functional form of BMP-2 is a disulflde-linked homodimer and about 26 kDa The precursor of BMP-2 is 259 a.a., containing the 23 a.a. N-terminal signal sequence which will be cleaved by a furin-type protease to form the mature peptide. 公司简介 上海怡淼化学科技有限公司,是一家...