Amino acid sequence of protein with atpase (adenosine triphosphatase) activity; viricides; antibodies; probes; primers; antisense agentsdoi:US6365372 B1A protein, SRCAP, is provided. The protein is capable of co-activating CREB binding protein (CBP) mediated transcription, as well as activating ...
This, coupled with the occurrence of OMP only in mature olfactory neurons of many vertebrate species, suggests that this protein has a unique function in the metabolism of these neurons. 展开 关键词: Animals Rats Carbohydrates Nerve Tissue Proteins Acetylation Amino Acid Sequence Olfactory Marker ...
39、roteins, the small chain is invariant but the amino acid sequence of the chain exhibits a high degree of variability, localized in specific domains of the protein that appear on the outside of the cell. Each human produces up to six different chains for class I MHC proteins.,The groov...
We present here a novel hierarchical PCA-EELM (principal component analysis-ensemble extreme learning machine) model to predict protein-protein interactions only using the information of protein sequences. In the proposed method, 11188 protein pairs retrieved from the DIP database were encoded into fe...
Primary Structure: The primary structure of a protein is its amino acid sequence. This amino acid sequence is determined by the base sequence of the gene which codes for the protein. Secondary Structure: Secondary structures have α-helices and β-pleated sheets. These form as a result of hydr...
Predicting protein structures from amino acid sequences used to be difficult and error prone. This changed in 2021 when AlphaFold2 reported near-experimental accuracy for most single-domain proteins. We look back on this breakthrough, discuss its effect on the field, and highlight AlphaFold3, a...
Currently, proteins of stable three-dimensional structures are almost all natural ones, whose amino acid sequences are results of long-time natural evolution. When structures and functions of natural proteins fail to fulfill industrial or biomedical needs, it is needed to design proteins to provide ...
Analysis of protein function and its prediction from amino acid sequence. Proteins: Struct. Funct. Bioinforma. 79, 2086–2096 (2011). Article CAS MATH Google Scholar Madani, A. et al. Large language models generate functional protein sequences across diverse families. Nat. Biotechnol. 41, ...
A unique cornea-associated antigen (CO-Ag) has been purified previously from stromal extracts. The protein is the target for autoantibodies in patients with Mooren's ulcer. In this study, the amino acid sequence of CO-Ag was analyzed and the structure-function properties of CO-Ag was determine...
We have purified one of the small proteins which occurs in a relatively large amount and have determined its amino acid sequence. The protein is characterized by a high lysine content; in the N-terminal region the lysine residues occur in an alternating order: X-K-X-K-X-K-X-K. The ...