Predict accurate, 3D models of proteins, using a combination of threading and ab initio protein structure prediction technologies with NovaFold. Learn here!
SWISS-MODEL 从序列模建结构 http://www.expasy.org/swissmod/SWISS-MODEL.html SWISS-3DIMAGE 三维结构图示 http://us.expasy.org/sw3d/ DSSP 蛋白质二级结构参数 http://www.cmbi.kun.nl/gv/dssp/ FSSP 已知空间结构的蛋白质家族 http://www.ebi.ac.uk/dali/fssp/fssp.html SCOP 蛋白质分类数据库 ht...
3D AB off-lattice modelThree-dimensional protein spatial structure prediction with the amino acid sequence can be converted to a global optimization problem of a multi-variable and multimodal function. This article uses an improved hybrid optimization algorithm named BSA-TS algorithm which combines ...
NuFold: end-to-end approach for RNA tertiary structure prediction with flexible nucleobase center representation The 3D structure of RNA is crucial for unraveling its functions. Here, the authors developed NuFold, an end-to-end deep learning-based approach that predicts all-atom RNA 3D structure...
欧几里得变化,来对氨基酸结构的3D结构进行建模 结构模块,结构调整变换8次,类似于LSTM training with labelled and unlabelled data 两个额外的技术 第一个是使用没有标号的数据,噪声的学生结构自蒸馏方法,把模型的标号好的数据再作为训练数据,用了噪声的trick ...
整体结构上模型的学习流程是‘1D’->'2D'->'3D'->优化 笔者把上述模型学习的过程称之为‘结构学习相变’ 这几乎是所有模型在学习过程中都会出现的现象,模型不会像我们认为的那样每样都学点,然后共同优化,而是先去优化某一类占据优化的情况(例如先学习某一类二级结构或者从2D学习到3D,而不是直接从3D开始优化) ...
3D Protein Structure Prediction with Genetic Tabu Search Algorithm in Off-Lattice AB Model A novel hybrid algorithm GATS (Genetic Tabu Search), which combines Genetic Algorithm (GA) and Tabu Search (TS) Algorithm, is presented for dealing with mu... T Wang,X Zhang - International Symposium on...
to learning 3d protein structure for interface prediction9695端到学习三维蛋白质结构以进行界面预测.pdf,End-to-End Learning on 3D Protein Structure for Interface Prediction Raphael J. L. Townshend Rishi Bedi Stanford University Stanford University raphael@
Recent advances in AI-based 3D protein structure prediction could help address health-related questions, but may also have far-reaching implications for evolution. Here we discuss the advantages and limitations of high-quality 3D structural predictions by AlphaFold2 in unravelling the relationship between...
we need to find if the similar sequence has 3D structure information yet, if yes, we can use 3D comparative modeling and then finish the 3D structure Prediction of the target sequence.第三,如果在数据库中并没有与目标序列相类似的已知序列的三维结构信息,则需要做进一步的蛋白质家族,域,或聚类分析...