In vitro generation of neuromesodermal progenitors reveals distinct roles for Wnt signalling in the specification of spinal cord and paraxial mesoderm identity. PLoS Biol. 12, e1001937 (2014). Article Google Scholar Okamoto, K. et al. A two-step mechanism for TRF2-mediated chromosome-end ...
most of them are type I, the cell body extends a peripheral process towards the organ of Corti, and a central process to the cochlear nucleus, which is responsible for transmitting auditory information from the inner hair cell (IHCs) to the ...
At the present time, methods to minimize the amount of scar tissue include the use of autogenous fat grafts, gelatin foams or sponges, or microfibullary collagen as an interposing protective layer between the spinal dura and the adjacent viscera. Other biological substances and chemical compounds ...
Moreover, dysfunction of organ-to-brain communication can be lethal. One of the most fundamental functions of the vagus nerve is to provide the first line of defense that protects the airways from injury. Defects in vagally mediated reflexes in the upper airways cause some of the most ...
Cochlear implants can directly activate the auditory system’s primary sensory neurons, the spiral ganglion neurons (SGNs), via circumvention of defective cochlear hair cells. This bypass restores auditory input to the brainstem. SGN loss etiologies are complex, with limited mammalian regeneration. Prote...
controls received a median cumulative dose of 48 mg/m2(IQR: 27.0–65.0) and 45 mg/m2(IQR: 18.0–64.5), respectively. Table1summarizes the clinical and demographic characteristics of the current cohort, and Supplementary Fig.1(CONSORT diagram) provides a comprehensive overview of included ...
Recent advances in cochlear implantology are exemplified by novel functional strategies such as bimodal electroacoustic stimulation, in which the patient has intact low-frequency hearing and profound high-frequency hearing pre-operatively. Therefore, the synergistic restoration of dysfunctional cochlear hair ...
Astragali Radix (AR) is a common Chinese medicine and food. This article aims to reveal the active role of AR in treating Type 2 diabetes mellitus (T2DM) and its renal protective mechanism. The hypoglycemic active fraction was screened by α-glucosidase and identified by UPLC-QE-Orbitrap-MS ...