Expression of RHBDL4 in presence of proteasome inhibitors increased secretion even further (Fig. 2e), indicating that turnover of proTGFαby the ERAD pathway and the RHBDL4-induced ER export are based on two independent mechanisms. ER export and non-canonical secretion of proTGFα are ...
Expression of RHBDL4 in presence of proteasome inhibitors increased secretion even further (Fig. 2e), indicating that turnover of proTGFα by the ERAD pathway and the RHBDL4-induced ER export are based on two independent mechanisms. ER export and non-canonical secretion of proTGFα are ...
Protease inhibitors (PI) blocking the catalytic activity of PR and disrupting the viral replication cycle have been used as a part of the combined ART since the late 1990s [32]. With the development of non-nucleoside reverse transcriptase inhibitor (NNRTI) class drugs, and more recently, ...
For the detection of Cdk1 and Cdk9 protein, western blot analysis was performed according to the previous method described in Reference [6]. Rpl7 was used as loading control. 2.7. Phosphatase Treatment The materials immunoprecipitated using rat anti-medaka Pgr antibody were incubated with or ...