PSACheck enables men to have the test performed and provides all the necessary support and guidance should the test flag anything of concern. An early PSA test as a ‘marker in the sand’ is very useful and can
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The use of membrane test kits for detecting prostate specific antigen (PSA) during the forensic identification of semen has become a routine procedure in forensic labs across North America. During the validation of the Seratec PSA Semiquant membrane test kit (Gesellschaft fr Biotechnologie, Germany)...
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Genetic variation at the 19q13.3 KLK locus is linked with prostate cancer susceptibility in men. The non-synonymous KLK3 single nucleotide polymorphism (SNP), rs17632542 (c.536 T > C; Ile163Thr-substitution in PSA) is associated with reduced
Replicative immortality is a hallmark of cancer, and can be achieved through telomere lengthening and maintenance. Although the role of telomere length in cancer has been well studied, its association to genomic features is less well known. Here, we repo
1 Since the beginning of the screening era for prostate-specific antigen (PSA) the detection rate of PCa has increased, resulting in a more frequent detection of indolent cancers. Conversely, the increasing incidence of PCa has reinforced the need to distinguish indolent cases from aggressive ...
Utilization of prostate-specific antigen (PSA) as a surrogate biomarker results in earlier diagnosis of the disease [2]. Localized disease can be cured with radical prostatectomy or radiotherapy [3]. However, patients with advanced or bulky local disease are at increased risk of treatment failure ...
In PC with BR after primary therapy, conventional imaging techniques have a low detection rate at the PSA levels at which targeted therapy with curative intent, such as salvage radiotherapy is effective. A magnitude of data indicate that68Ga-PSMA-PET can detect recurrent PC or small LN metastase...
Seminal plasma was diluted 1000 times for estimation of t-PSA using an ELISA based kit from Weldon Biotech (Cat No: t-PSA 118WB). Absorbance was measured on µQuant (Bio-Tek Instruments Inc.) and analyzed using KC Junior software. Statistical analysis Chi square analysis was used to ...