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One such biomarker is the Prostate Health Index (phi), which was recently approved by the FDA. Phi combines total serum PSA, free PSA and [-2]proPSA using the mathematical formula: ([-2]proPSAn-free PSA) x VPSA. A large pivotal prospective trial of phi in the USA showed that it ...
Prostate health index (PHI) The PHI test is a serum-based analysis, developed by Beckman Coulter Inc. and the National Cancer Institute-Early Detection Research Network. The biomarkers included in the PHI are [-2] proPSA, free PSA (fPSA), and total PSA (tPSA). These individual values are...
Prostate health index (PHI) The PHI test is a serum-based analysis, developed by Beckman Coulter Inc. and the National Cancer Institute-Early Detection Research Network. The biomarkers included in the PHI are [-2] proPSA, free PSA (fPSA), and total PSA (tPSA). These individual values are...
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28 Prostate Health Index (PHI) was calculated using the formula ([−2]proPSA/free PSA) × √(PSA). Comparative analysis included PSA, the Prostate Cancer Prevention Trial risk calculator,21 PHI, the derived multiplex 2-gene and 3-gene models, MPS,19 MPS2, and MPS2+. The primary...
The PHI (prostate health index) defined by the formula [([-2]proPSA/free PSA) ×√total PSA] was developed for prognostic purposes [149,187]. The PHI, compared to other PSA-related tests, has been shown to better differentiate PC from benign prostatic hyperplasia, and thus to prevent ...
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