摘要: Despite significant elevations in serum total and free testosterone, healthy young men do not demonstrate increased serum or semen PSA levels, or increased prostate volume in response to exogenous testosterone injections.关键词: Humans Prostate Semen Testosterone Prostate-Specific Antigen ...
et al. MR imaging of the prostate gland: normal anatomy. Am. J. Roentgenol. 148, 51–58 (1987). CAS Google Scholar Wang, L. et al. Assessment of biologic aggressiveness of prostate cancer: correlation of MR signal intensity with Gleason grade after radical prostatectomy. Radiology 246, ...
Note adjacent normal prostate gland (arrowheads). (F) Perineural microacinar neoplastic infiltrates exhibiting strong HDAC3 expression in approximately 70% of tumour cell nuclei. Full size image Strong nuclear HDAC1, HDAC2 and HDAC3 immunoreactivity was seen in most adenocarcinomas (Figure 1, ...
The prostate gland is the most common site of cancer and the second leading cause of cancer death in American men. Recent emerging molecular biological technologies help us to know that epigenetic alterations such as DNA methylation within the regulatory
SGOT/AST = 82 (normal less than 40) Gamma-GT = 436 (normal less than 71) Alkaline phosphatase = 513 (normal 40 – 129) Creatinine = 2.69 (normal 0.67 – 1.17) eGFR = 23.64 (less than 15 means kidney failure). According to the doctor the patient has progressing mCRPC (failed NHA, ...
Corresponding regions on MR images and histologic specimens were defined by using anatomically defined segments in peripheral zone (PZ) and central gland tissue. Cancer and normal PZ regions were identified at histopathologic analysis. Each MR parameter-histologic tissue component pair was assessed by ...
, volume) after intraprostatic administration.96 This is particularly relevant to localized prostate cancer, which is known to be a multi-focal disease. In terms of enhancing the possible systemic effects of gene therapy, vectors armed with immune-stimulatory genes and prostate-specific antigens are...
For the purposes of radiotherapy planning in prostate cancer, radiation oncologists consider the prostate gland to be the target volume, while the remaining structures are delineated as OARs. In the case of head and neck cancer, we used a subset of OAR structures defined by a panel of ...
that many SV genes are not captured by t-test (Fig.S1A) and that SV genes need not to be restricted to tumor vs. normal comparisona priori; e.g., COX7A2 is expressed in both tumor and prostate intraepithelial neoplasia (PIN) regions and depleted in normal prostate gland (Figs.1Cand2...
partial volume effects, tissue heterogeneity, and the lower number of representative slices in comparison to the mid-gland. This limitation might be overcome by augmenting the last few slices of the upper and lower prostate and training the network on the whole set with the augmented slices so ...