Testicular testosterone is locally metabolized to the more potent androgen DHT in the prostate gland. In normal men, medical castration using the LHRH agonist reduces systemic levels of androgens, but 1 month later, intraprostatic androgens were only reduced to 20% to 30% of co...
Biochemical relapse-free survival (bRFS) was defined as the elapsed time from study enrolment to PSA relapse (by the American Urological Association definition of PSA ≥0.2 ng/mL on two consecutive readings) and/or death due to any cause [21]. Time-to-event analysis was performed using ...
Region_Of_Interest • prostate cancer Technology Type(s) Multiparametric Magnetic Resonance Imaging • image segmentation • visual observation method Factor Type(s) temporal_interval Sample Characteristic(s) Homo sapiens • prostate gland 1Brigham and Women's Hospital, Harvard Medical School, ...
Because the applicator and neighboring anatomy serve as the reference frame for brachytherapy, image fusion is normally done according to either the applicator or the prostate gland. Image fusion between MRI and US may be needed during US-based implantation (e.g., MRI-informed brachytherapy or MRI...
For all CT/MR scans, the treating investigator delineated the following structures: clinical target volume (CTV: prostate plus proximal 1 cm of the seminal vesicles, measured cephalo-caudal from the seminal vesicle origin), planning target volume (PTV: 5-10 mm per institutional definition, except...
5.2.9.4.4 Definition of extraprostatic extension 42 第4页4 PROSTATE CANCER - LIMITED UPDATE MARCH 2022 5.2.9.4.5 PCa volume 43 5.2.9.4.6 Surgical margin status 43 5.3 Diagnosis - Clinical Staging 43 5.3.1 T-staging 43 5.3.1.1 TRUS 43 5.3.1.2 MRI 43 5.3.2 N-staging 44 5.3.2.1 Compu...
Swelling of the prostate gland by permanent brachytherapy may affect seed migration. Jap J Clin Oncol. 2010;40:1159–65. Article Google Scholar Sugawara A, Nakashima J, Kunieda E, Nagata H, Mizuno R, Seki S, et al. Incidence of seed migration to the chest, abdomen, and pelvis after ...
Definition of seed migration Although the transfer of seeds out of the prostate is referred to as seed migration, only the transfer of seeds to the lung is regarded as seed migration in many cases. In the present study, seed migration was defined as “an event in which seeds enter a blood...
Pattern 5 can appear as three forms—single cells, sheets of cells without histological evidence of gland formation and comedocarcinoma (Figs. 1 and 2). Sign in to download full-size image Fig. 1. Current modified schematic Gleason diagram (courtesy of David Grignon, Indiana University Medical ...
(task-specific), hence the terminology “sequential”. The sequence of tasks was determined based on the natural history of prostate cancer (see Fig.1b). See Supplementary Fig.1for the correlation between each pair of tasks. Created in BioRender. Larose, M. (2024)https://BioRender.com/g04...