Medications such asketoconazole(Nizoral),cimetidine(Tagamet),diltiazem(Cardizem),verapamil(Calan),ritonavir(Norvir) andclarithromycin(Biaxin) slow down the breakdown of dutasteride. This may lead to increased levels of dutasteride in the body, increasing side effects such as decreased libido,erectile dys...
THE PROSTATE MEDICINE CUPBOARD; Your Complete Guide to the Treatments Available, How They Work and What Side-Effects to ExpectByline: ROGER DOBSON BEING one of the 21,000 men diagnosed with prostate cancer in Britain...Dobson, Roger
Prostate cancer is usually a very slow-growingcancer, often causing no symptoms until it is in an advanced stage. Most men with prostatecancerdie of other causes and many never know that they have the disease. But once prostatecancerbegins to grow quickly or spreads outside the prostate, it...
Prostate cancer is usually a very slow-growingcancer, often causing no symptoms until it is in an advanced stage. Most men with prostatecancerdie of other causes and many never know that they have the disease. But once prostatecancerbegins to grow quickly or spreads outside the prostate, it...
Note: 1.TURPTorTransurethral Resection of Prostate Tumoris a surgical procedure used to remove part of an enlarged prostate. This procedure is a less invasive option to an open prostatectomy and is used in cases where the prostate is not large enough to necessitate complete removal. During TURP...
LCP cells were also used in a xenograft and treated with T0070907 whereupon 4/7 tumours could no longer be detected indicating a complete regression. This inhibition of growth was shown to be through conventional PPARγ signalling with fatty acid synthesis genes FASN and ACACA being downregulated,...
“PSMA-I&T”, with two phenyl substitutions in the side chain, but also based on the DUPA motif. This compound was labeled both with68Ga and177Lu for theranostic applications and was shown to efficiently target PSMA-expressing tumors in PC patients. Recently, the same group has reported ...
The MPC transports pyruvate from the cytosol to the mitochondria, where it can be oxidized to fuel the TCA cycle26. As basal-to-luminal differentiation is associated with increased pyruvate oxidation, we investigated the effects of inhibiting the MPC with the small-molecule MPC inhibitor UK5099....
Probe 10 (0.1 mg probe 10 in 100 μL saline, i.v.) could clearly delineate tumor margins in mice xenografted with U87MG tumors, which benefited the complete resection of tumors during the surgery. During the intraoperative fluorescence-guided surgeries in human beings, probe 10 (1.0 mg ...
(Dojindo Molecular Technologies, Japan) was used to detect cell viability. Simply, the cells were seeded in 100 μl of complete medium at a concentration of 2000 cells per well in a 96-well plate for 24 h, and then treated according to the conditions indicated in figure legends. Then...