The purpose of this study was to define the monocyte/macrophage population prevalent in skeletal tumors, explore a mechanism employed in supporting prostate cancer (PCa) skeletal metastasis, and examine a novel therapeutic target. Phagocytic CD68+ cells were found to correlate with Gleason score in ...
This is one reality that everyone of us need to know and accept –cure may be unnecessary, or cure may not be possible.I am reminded of a friend, Steve – a British engineer who chose to settle down in Bangkok. He too had prostate cancer. He went to Singapore and was put on Intermi...
Markers which showed potential difference (p < 0.05) between DRE and FV are shown in red and markers which did not (p > 0.05) are shown in blue Full size image Comparison of urine DNA methylation and Gleason score and tumor volume The histopathological findings (Gleason score, # ...
Objective To analyze the relationship between serum prostate specific antigen(PSA) level and Gleason score in patients with prostate cancer. Methods The clinical data of 106 patients with prostate cancer admitted to our hospital were retrospectively analyzed,and the serum PSA and Gleason scores were co...
Gleason Scale Levels Low Grade (well differentiated): 4 or less. Intermediate Grade (moderately differentiated): 4 to 7. High Grade (poorly differentiated): 8 to 10. Low Gleason Score: 4 or Less Your biopsy test results indicate prostate cancer cells that still look like regular prostate cells...
BRF1 is a rate-limiting factor for RNA Polymerase III-mediated transcription and is elevated in numerous cancers. Here, we report that elevated levels of BRF1 associate with poor prognosis in human prostate cancer. In vitro studies in human prostate canc
WebMD's slideshow covers prostate cancer: who's at risk, symptoms, tests, staging, treatments, survival, and foods that may help lower your risk for prostate cancer.
Prostate cancer (PCa) is the second leading cause of death in men and the most common tumor in men in the western hemisphere1. Therapeutic strategies are highly dependent on the assessment of the lymph node (LN) status, since it affects the therapy regimen and overall prognosis in newly diag...
Effect of prostate radiotherapy on failure-free survival across baseline factors in low and high metastatic burden subgroups. eReferences. Supplement 3. Data Sharing Statement 1. Parker CC, James ND, Brawley CD, et al; Systemic Therapy for Advanced or Metastatic Prostate cancer: Evaluati...
A total of 1,335 patients with prostate cancer diagnosed between 2009 and 2015 were enrolled from the Second Affiliated Hospital of Zhejiang University School of Medicine. The survival of patients with different prostate-specific antigen (PSA) levels, Gleason scores, marital statuses and bone ...