but which of these risk factors cause a prostate cell to become cancerous is not fully known. For a cancer to develop, changes must occur in the chemicals that make up the DNA, which makes up the genes in the cell. The genes control how the cell ...
but which of these risk factors cause a prostate cell to become cancerous is not fully known. For a cancer to develop, changes must occur in the chemicals that make up the DNA, which makes up the genes in the cell. The genes control how the cell ...
CONCLUSION We were able to demonstrate a difference in the prognosis between a TRUS stage T3 and a TRUS stage T1 or T2. The prognostic value of TRUS may depend on the definition of T3 disease, in terms of extension to the capsule. We recommend that TRUS T3 should only include tumors ...
Prostate cancer (PC) is an epithelial malignancy occurring in the prostate. PC ranks second in incidence among all male malignancies globally by the latest statistics from the World Health Organization. Notably, China has seen a more rapid increase in PC incidence compared to developed European and...
cell carcinomata, and neuroendocrine tumors (World Health Organization [WHO] classification 2016) do occur and generally have a worse prognosis. Rarely, non-epithelial malignant transformation results in lymphomas and sarcomas, more commonly following radiation exposure for previous, eg, rectal cancer.[...
Reliable prognostic biomarkers to distinguish indolent from aggressive prostate cancer (PCa) are lacking. Many studies investigated microRNAs (miRs) as PCa prognostic biomarkers, often reporting inconsistent findings. We present a systematic review of th
are used to generate a histological sum score (summed from scores of two most dominant patterns), which can range from 2 to 10 [32]. Gleason grading of the cancer is the most widely used, and accepted histopathological method for providing information about the prognosis of prostate cancer. ...
Both TP53 and AR aberrations indicate a worse prognosis in metastatic androgen responsive prostate cancer [20]. Here, we aimed to explore common and selective effects of 12C-ion and photon irradiation with respect to DNA-damage and gene regulation, as reflected by alterations of mRNA levels in ...
Docetaxel resistance represents a significant obstacle in the treatment of prostate cancer. The intricate interplay between cytokine signalling pathways and transcriptional control mechanisms in cancer cells contributes to chemotherapeutic resistance, ye
Prostatecanceris cancerof prostate gland. The prostate gland is a walnut-sized gland present only in men, found in the pelvis below the bladder. The prostate gland wraps around the urethra (the tube through which urine exits the body) and lies in front of the rectum. The prostate gland sec...