Although newer clinicopathologic risk-stratification systems have been created, three variables remain at their core—Gleason score, T-stage, and PSA9. More recently, tissue-based genomic biomarkers10 have demonstrated superior prognostic performance. However, nearly all of these tests lack validation in...
Stage C Prostate Cancerstagec
MP05-05 LONG-TERM OUTCOMES OF MEN WITH STAGE PT3B PROSTATE CANCER DIAGNOSED BY SEMINAL VESICLE BIOPSY AND TREATED BY BRACHYTHERAPY AND EXTERNAL BEAM IRRADIATION Patients who present with localized and locally advanced prostate cancer may be candidates for prostate brachytherapy. We evaluated the treatme...
Fig. 1: The Progression of Prostate Cancer. Flow diagram depicting the progression and treatment of PCa from low grade, hormone-sensitive PCa to late stage, hormone-resistant tumors. Full size image The development of N-glycan imaging mass spectrometry in 2013 (IMS)17,18 has provided great adv...
Stage I: Cancer cells are limited to within the prostate gland, usually in half or less of one side. Stage II: The cancer is still contained within the prostate but is more likely to spread. It may be in the supportive tissue that surrounds the gland. Stages I and II are considered lo...
To determine whether genetic changes are markers of cancer progression and patient survival in Stage T(2-3)N(1-3)M(0) prostatic carcinoma, we compared 26 patients who died of tumor relapse after prostatectomy and lymphadenectomy (case group) with 26 matched patients who were alive at the time...
Prostate cancer is usually a very slow-growingcancer, often causing no symptoms until it is in an advanced stage. Most men with prostatecancerdie of other causes and many never know that they have the disease. But once prostatecancerbegins to grow quickly or spreads outside the prostate, it...
The potential for normal tissue dose reduction with neoadjuvant hormonal therapy in conformal treatment planning for stage C prostate cancer Yang G, Chen G, Ray PEA (1995) The potential for normal tissue dose reduc- tion with neo-adjuvant hormonal therapy in conformal treatment planning for... ...
Perineural invasion (PNI), a pathologic feature defined as cancer cell invasion in, around, and through nerves, is an indicator of poor prognosis and survival in prostate cancer (PC). Despite widespread recognition of the clinical significance of PNI, the molecular mechanisms are largely unknown. ...
To determine whether genetic changes are markers of cancer progression and patient survival in Stage T2–3N1–3M0 prostatic carcinoma, we compared 26 patients who died of tumor relapse after prostatectomy and lymphadenectomy (case group) with 26 matched patients who were alive at the time of the ...