Prostate cancer (PC) is an epithelial malignancy occurring in the prostate. PC ranks second in incidence among all male malignancies globally by the latest statistics from the World Health Organization. Notably, China has seen a more rapid increase in PC incidence compared to developed European and...
Prostate cancer is comprised nearly always of adenocarcinomacells -- cells that arise from glandular tissue. Cancer cells are named according to the organ in which they originate no matter where in the body we find such cells. Thus, if prostate cancer cells spread in the body to the bones, ...
Prostate cancer is comprised nearly always of adenocarcinomacells -- cells that arise from glandular tissue. Cancer cells are named according to the organ in which they originate no matter where in the body we find such cells. Thus, if prostate cancer cells spread in the body to the bones, ...
OBJECTIVES: To characterize testosterone profile changes over time in a cohort of prostate cancer (PCa) patients managed with active surveillance (AS) and to assess its correlation with the initial disease characteristics and further progression. METHODS: We conducted retrospective chart review of PCa ...
Both patient and physician should maintain a PSA flow chart that records all PSA values, the date of measurement, and the PSA assay used. Patients with persistent elevated PSA levels may benefit from further evaluation using other PSA parameters to improve prostate cancer detection and assessment ...
The randomized phase 3 CHART trial (NCT03520478) revealed that rezvilutamide (REZ) plus androgen deprivation therapy (ADT) in high-volume, metastatic, hormone-sensitive prostate cancer (mHSPC) significantly enhanced radiographic progression-free and overall survival than bicalutamide (BIC)-ADT. Accordin...
Witte1,2,14 Prostate-specific antigen (PSA) levels have been used for detection and surveillance of prostate cancer (PCa). However, factors other than PCa—such as genetics—can impact PSA. Here we present findings from a genome-wide association study (GWAS) of PSA in 28,503 Kaiser ...
A flow chart in this study workflow. PSA: prostate-specific antigen; PC: prostate cancer; DCE-MRI: dynamic contrast-enhanced MRI; DWI: diffusion-weighted imaging; PZ: peripheral zone; TZ: transition zone; PI-RADS: Prostate Imaging Reporting and Data System Full size image 2.6 Statistical analys...
Background: The prostate-specific antigen (PSA) is an important cancer biomarker that is commonly utilized in the diagnosis of prostate cancer. The development of a PSA determination technique that is rapid, simple, and inexpensive, in addition to highly accurate, sensitive, and selective, remains...
Share experiences with other prostate cancer patients. Watchful Waiting Watchful Waiting Also called expectant therapy, patient undergoes careful monitoring instead of more aggressive therapy. Expectant Therapy Patients Recommended to those with low Gleason and PSA levels, and nonpalpable tumors. ...