Providers who spent more than 20 minutes counseling patients were more likely to use a risk estimation tool (OR 2.2, p <0.01). After the prostate cancer diagnosis 70% of providers used a risk estimation tools to guide treatment recommendations. The total time spent counseling a patient (...
A new prognostic tool developed by researchers from the UCLA Jonsson Comprehensive Cancer Center and five other institutions helps predict which men with advanced metastatic prostate cancer will respond favorably to a novel targeted therapy. The tool, described in a study published today inLancet Oncolo...
Genetic testing, to identify pathogenic or likely pathogenic variants in prostate cancer, is valuable in guiding treatment decisions for men with prostate cancer and to inform cancer prevention and early detection options for their immediate blood relatives. There are various guidelines and consensus stat...
Building upon previous research, an international team led by scientists at University of California San Diego School of Medicine, has validated a more inclusive and comprehensive genetic tool for predicting age of onset of aggressive prostate cancer, a disease that killed more than 33,000 American ...
Six transmembrane epithelial antigen of the prostate 1 (STEAP1) is a cell surface antigen for therapeutic targeting in prostate cancer. Here, we ...(Supplementary Fig.5c). Prior analysis using another in silico hidden Markov model-based topology prediction tool TMHMM47had also suggested that this...
To improve preoperative risk stratification for prostate cancer (PCa) by incorporating multiparametric MRI (mpMRI) features into risk stratification tools
Ltd. has synthesized proteolysis targeting chimeras (PROTACs) comprising an E3 ubiquitin ligase coupled to an androgen receptor targeting moiety via a linker reported to be useful for the treatment of spinal and bulbar muscular atrophy, prostate and breast cancer.Read More Cancer Etern Biopharma ...
Personalized Prediction of Tumor Response and Cancer Progression on Prostate Needle Biopsy - ScienceDirect Personalized prediction of tumor response and cancer progression on prostate needle biopsy. J Urol. Jul 2009;182(1):125-132. PMID 19450827... Michael J. Donovan a,Faisal M. Khan a,Gerardo...
Kaplan–Meier analysis for overall survival (OS) of second primary malignancy (SPM) after prostate cancer (PCa) based on risk score in the training set (p < 0.001) (A) and the validation set (p < 0.001) (B), age (p < 0.001) (C), stage T (p < 0.001) (D),...
(mAbs) to assess the prostate cancer (PCa) diagnostic utility of different PSA molecular forms,...(RCs) prediction models, developed to assess patient’s individual PCa risk, which show a ...its reliability as screening tool for PCa remains controversial due to its lack of specificity. ...