Two randomized controlled trials (RCTs) recently published in European Urology—representing the largest studies of their kind—have tackled the issue of how best to deliver exercise interventions to men with prostate cancer on long-term androgen deprivation therapy (ADT)....
heimer ’ s disease News ADT in prostate cancer and risk of Alzheimer ’ s diseaseNews ADT in prostate cancer and risk of Alzheimer ’ s diseaseBagcchi, Sanjeet
450 men completed the Expanded Prostate Cancer Index Composite-26 questionnaire before and shortly after starting neoadjuvant ADT, 71 of whom received ADT prior to radiotherapy. The significant QOL effects of this therapy should be weighed carefully against potential clinical benefit....
A natural history of weight change in men with prostate cancer on androgen-deprivation therapy (ADT): results from the Shared Equal Access Regional Cancer Hospital (SEARCH) database. BJU Int. 2011; 107 :924–8.Kim HS, Moreira DM, Smith MR, Presti JC, Jr., Aronson WJ, et al.: A ...
ADT not linked to excess CV mortality in prostate cancer.ADT not linked to excess CV mortality in prostate cancer.The article discusses research on the link between androgen-deprivation therapy (ADT) and the risk of cardiovascular (CV) death in men with unfavourable-risk prostate cancer, referenci...
For patients with localizedprostate cancerwho undergo radiotherapy, giving androgen deprivation therapy (ADT) in the adjuvant setting leads to better oncologic outcomes than occur with up-front neoadjuvant ADT, which is how it is usually given. ...
Laurence Klotz. (2013) Prostate cancer: Intermittent ADT—tales from a 27-year odyssey. Nature Reviews Urology 10 , 372-374 /LaurenceKlotz. (2013) Prostate cancer: Intermittent ADT—tales from a 27-year odyssey. Nature Reviews Urology 10 , 372-374 /...
前列腺癌(prostate cancer) 是老年男性的常见恶性肿瘤,其发病率有明显的地区和种族差异。全球范围内,欧美国家前列腺癌发病率最高,居男性实体恶性肿瘤首位,亚洲前列腺癌发病率远低于欧美。我国前列腺癌发病率近年来呈显著上升态势,这与人均寿命的延长、饮食结构的改变以及诊断技术的...
Almost all men with ADT-treated metastatic prostate cancer will develop castrate-resistant disease, if they live long enough. There are now many options for the treatment of castrate-resistant prostate cancer, including first- and second-line chemotherapy, immunotherapy (sipuleucel-T), further anti-...
The mangrove killifish Rivulus marmoratus, a neotropical fish in the order Cyprinodontiformes, is the only known obligatorily selfing, synchronous hermaphroditic vertebrate. To shed light on its population structure and the origin of hermaphroditism, major histocompatibility complex (Mhc) class I genes...