Hormone treatment is more appropriate for locally advanced disease, and is a valuable non-surgical treatment for bladder outflow obstruction due to prostate cancer. A significant proportion of elderly men with prostate cancer still die from other diseases. Hormone refractory disease in the elderly ...
Hormone treatment is more appropriate for locally advanced disease, and is a valuable non-surgical treatment for bladder outflow obstruction due to prostate cancer. A significant proportion of elderly men with prostate cancer still die from other diseases. Hormone refractory disease in the elderly ...
and it is one of the leading causes of death attributable to cancer in men above 60 years of age. Nonetheless, many prostate cancers have a relatively mild severity with limited impact on life expectancy. For this reason, prostate cancer treatment has to ...
treatmentvasculitisProstate cancer presents a growing health problem in Western societies as longevity increases. It is characteristically a disease of elderly men associated with the development of osteoblastic bone metastases and initial hormone responsiveness to androgen deprivation. Previously regarded as a...
Current status and future perspective on the management of metastatic castration-sensitive prostate cancer Masatoshi EtoLeandro BlasMasaki Shiota Jan 2022 Since 1941, the standard treatment for metastatic castration-sensitive prostate cancer (mCSPC) was androgen deprivation therapy (ADT) by surgical or medi...
Prostate cancer presents a growing health problem in Western societies as longevity increases. It is characteristically a disease of elderly men associated with the development of osteoblastic bone metastases and initial hormone responsiveness to androgen deprivation. Previously regarded as a Cinderella of ...
Most patients with prostatic cancer present with either locally advanced or metastatic disease, for which palliative endocrine therapies are the first-line treatment. The increasingly sophisticated and selective hormonal methods available today, such as the longer-acting formulations of luteinizing hormone-...
prostate cancer becomes resistant to treatment when patients fail to respond to hormone therapy, radiation, andmultiplerounds of untargeted chemotherapy. in certain cases, these maximum therapeutic doses of untargeted chemoinundate thecancer cells, triggering their ability to pump out some of the anti-...
Beta-catenin-related anomalies in apoptosis-resistant and hormone-refractory prostate cancer cells. Clin Cancer Res. 2003;9:1801–7. PubMed Google Scholar Chen G, Shukeir N, Potti A, Sircar K, Aprikian A, Goltzman D, et al. Up-regulation of Wnt-1 and beta-catenin production in ...
1h–j).These results suggest that S.C exhibits anti-tumor properties not only in hormone-sensitive prostate cancer cells but also in castration-resistant prostate cancer cells. Fig. 1 S.C suppresses prostate cancer cell viability, colony formation and migration abilities. a–e Cell viability of ...