Meaning These findings suggest that a short, noncontrast MRI may have favorable performance characteristics as a community-based screening test. Abstract Importance Screening for prostate cancer using prostate-specific antigen (PSA) testing can lead to problems of underdiagnosis and overdiagnosis. Short,...
Prostate cancer is one of the most common forms of cancer and the third leading cause of cancer death in North America. As an integrated part of computer-aided detection (CAD) tools, diffusion-weighted magnetic resonance imaging (DWI) has been intensivel
This cluster randomized trial evaluates the effect of a single prostate-specific antigen (PSA) screening test on 10-year prostate cancer–specific
Analyses of PC biopsies from men in sub-Saharan Africa have revealed a significant proportion of high-grade tumors (Gleason score 8+). However, variations in healthcare access and differences in cancer case registration across countries limit the reliability of conclusions regarding the correlation ...
(prostate-specific antigen or PSA) produced by prostate cells. The PSA test may indicate a person has a higher chance of having prostate cancer but controversies about the test exist (see following slide). The patient and his doctor need to carefully consider the meaning and the use of these...
In February 2013, I have posted a similar case,Prostate-Bone Cancer– Part 1: PSA Came Tumbling Down: From 6,963 to 200 and Severe Pains Vanished.This is the story of a 72-year-old man from Surabaya, Indonesia. His prostate cancer had spread extensively to his back bone. I have the...
For instance, in Schroder, the rate of overdiagnosis was estimated to be 50%, while Hugosson also noted a high risk of overdiagnosis (6,7). This is important, as while these tests found prostate cancer, they alerted patients to a disease that may not kill them or even affect their ...
Study: PSA level changes important; Prostate cancer fatality rate seems linked to how rapidly test numbers fluctuateASSOCIATED PRESS
Lineage plasticity, the ability of a cell to alter its identity, is an increasingly common mechanism of adaptive resistance to targeted therapy in cancer. An archetypal example is the development of neuroendocrine prostate cancer (NEPC) after treatment of prostate adenocarcinoma (PRAD) with inhibitors...
Meaning In patients with prostate cancer, bone metastatic burden and metastasis location may be useful in predicting survival benefit from prostate RT. Abstract Importance Prostate radiotherapy (RT) improves survival in men with low-burden metastatic prostate cancer. However, owing to the dichotomized ...