and Kronenberg F. (2010) Somatic mutations throughout the entire mitochondrial genome are associated with elevated PSA levels in prostate cancer patients. Am. J. Hum. Genet., 87, 802-812.Kloss-Brandstatter, A., Schafer, G., Erhart, G., Huttenhofer, A., Coassin, S., Seifarth, C., ...
Middle-aged men with elevated PSA levels experienced an increased risk for lethal prostate cancer, according to the results of a nested case–control study. “We found that a single baseline PSA level measured during midlife predicted subsequent...
Prostate specific antigen(PSA) blood test: The PSA blood test measures the level of a protein found in the blood that is produced by the prostate gland and helps keep semen in liquid form. ThePSA testcan indicate an increased likelihood of prostate cancer if the PSA is at an increased or ...
Prostate specific antigen(PSA) blood test: The PSA blood test measures the level of a protein found in the blood that is produced by the prostate gland and helps keep semen in liquid form. ThePSA testcan indicate an increased likelihood of prostate cancer if the PSA is at an increased or ...
Previous research has shown that aberrant sphingolipid metabolism, which is evidenced by elevated levels of circulating ceramide, is associated with poor prognosis in patients with prostate cancer (PC). Work at the University of Adelaide has led to the establishment of a new syngeneic mouse model to...
Several conditions can lead to an elevated PSA level, not just prostate cancer.2 As men grow older, many are affected by prostatitis (inflammation of the prostate) or benign prostatic hyperplasia (BPH) (a non-cancerous enlargement of the prostate) that can...
An elevated PSA level may be caused by prostate cancer but can also be caused by other conditions, including an enlarged prostate (benign prostatic hyperplasia) and inflammation of the prostate (prostatitis). Some men without prostate cancer may therefore have positive screening results (ie, “...
Men with benign prostatic conditions (non-cancer [NC]) (Supplementary Data 1) included individuals with elevated serum PSA (sPSA) levels and benign prostatic hyperplasia (BPH; 44 patients; median sPSA 6.3 ng mL−1, range 1.7–11.9 ng mL−1) or no diagnosed prostate cancer on...
L. et al. Elevated levels of FOXA1 facilitate androgen receptor chromatin binding resulting in a CRPC-like phenotype. Oncogene (2013). Google Scholar Hornberg, E. et al. Expression of androgen receptor splice variants in prostate cancer bone metastases is associated with castration-resistance ...
If the PSA level is elevated (levels can depend upon your age, on the size of your prostate gland on examination, certain medications you may be taking, or recent sexual activity) or has increased significantly over time, further testing may be needed to rule out prostate cancer. ...