Prostate cancer is the second most common cancer in men worldwide and causes over 250,000 deaths each year1. Overtreatment of indolent disease also results in significant morbidity2. Common genetic alterations in prostate cancer include losses of NKX3.1 (8p21)3,4 and PTEN (10q23)5,6, gains...
Prostate cancer is the second most common cause of male cancer deaths in the United States. However, the full range of prostate cancer genomic alterations is incompletely characterized. Here we present the complete sequence of seven primary human prostate cancers and their paired normal counterparts. ...
affecting nearly 1.6 million individuals with more than 3,00,000 deaths worldwide [3]. Reports showed that it is the second most commonly identified cancer in males and the fifth major cause of cancer-related death [4]. In India, PC was one of the most frequently detected cancers in 2020...
e17086#Background:The survival benefit of upfront triplet therapy in the treatment of metastatic hormone-sensitive prostate cancer (mHSPC) has been demonstrated in two prospective randomised trials using a combination of androgen deprivation therapy (ADT), docetaxel and an androgen receptor signalling ...
Prevalence of Prostate Cancer Prostate cancer is one of the leading causes of death from malignant disease among men globally[1].New Cases and Deaths for 36 Cancers and All Cancers in Males in 2020Primary Risk Factors[2-3]Symptoms[4]
The American cancer society predicted that in 2022 around ∼ 268,490 new cases and around ∼ 34,500 new deaths because of PC in the USA [1]. PC comes under adenocarcinoma and is contemplated as non-cutaneous neoplasia [2]. The PC occurs by the mutation in prostate gland cells causing...
this cancer. The deaths due to prostate cancer in America stand second after deaths caused due to lung cancer. 1 in 9 men is diagnosed with prostate cancer. Prostate cancer affects mostly older men and has more prevalence in African-American men. Growing awareness among people and advancements ...
Current prostate cancer treatments are associated with life-threatening side effects, prompting the search for effective and safer alternatives. Aspilia pluriseta Schweinf. ex Engl. has previously shown anticancer activity in lung and liver cancer cell l
Prostate cancer (PCa) is one of the most common cancers in men around the world, second after lung, bronchus and trachea cancers1. In China, PCa incidence and mortality rates have been rapidly increasing, with an estimate of 60,300 new cases and 26,600 deaths in 2015 only2. Obesity is...
3. Prostate cancer is not an exception to this point4and it is one of the most common malignancies responsible for male cancer deaths in the western world4,5,7,8. The heterogeneous5, multifocal5,6nature of prostate cancer along with the late appearance of castration resistant7,8disease form...