cancer stem cellsc-Met protooncogenehepatocyte growth factor/scatter factorHGF/SFimmunophenotypekeratin 14, 5, and 18neuroendocrine factorsprimaryrecurrent and metastatic prostate cancerThe prostate stem cell concept described in this chapter was studied in our laboratory, where we provided experimental ...
Prostate cancer cells have robust telomerase activity and several commonly used prostate cancer cell lines show a significant TRAP signal (Fig. 1A). Similar to the results observed in primary tumor samples (data not shown), these cell lines have relatively short telomeres (Fig. 1B). The cell ...
sensitive prostate cancer cells; further studies demonstrated that the decreased cell proliferation was due to cellular apoptosis. The results of the present study suggested that the CRISPR/Cas system may be a useful therapeutic strategy for the treatment of prostate cancer. 文章引用产品 AP105 324 ...
with the rapid development of single-cell sequencing and spatial transcriptome technologies, researchers have gained a more intuitive and comprehensive understanding of the heterogeneity of prostate cancer. Tumour-associated epithelial cells; cancer-associated fibroblasts; the complexity of the immune microenvir...
causing robust cell death and apoptosis. SKI-178 impaired mitochondrial functions, causing mitochondrial depolarization, reactive oxygen species production and ATP depletion.SKI-178 potently inhibited SphK activity and induced ceramide production, without affecting SphK1/2 expression in prostate cancer cells....
Prostate cancer cells SEM ID: 245319058 收藏 加入清单 下载版权royaltystockphoto.com TIFF大小 34.3MB 格式JPG 以图搜图 大图:4000× 3000 像素·33.87 cm × 25.4 cm·300dpi·JPG 中图:1000× 750 像素·35.28 cm × 26.46 cm·72dpi·JPG 小图:500× 375 像素·17.64 cm × 13.23 cm·72dpi·JPG ...
Androgen receptor (AR) signaling is the central signal transduction pathway in prostate cancer. Many different epigenetic mechanisms affecting this critical pathway play a role in disease initiation and progression. This includes the presence of AR variants that are constitutively transcriptionally active, ...
Stem cellsProstate cancer is the most frequently diagnosed cancer in men. Despite recent advances in the detection of early prostate cancer there is little effective therapy for patients with locally advanced and/or metastatic disease. The majority of patients with advanced disease respond initially to...
Other studies have also shown that the PI3K/Akt/mTOR signaling pathway exerts an antiapoptotic effect and contributes to autophagic regulation in cancer cells59. However, how autophagy is related to the PI3K–AKT–mTOR pathway is not clear. Activated mTORC1 downregulates autophagy by phosphorylating ...
(b) 细胞株:前列腺癌细胞(prostate cancer cell line), 肾上腺皮质细胞株 (H295 cells)(a) 留置导管 (Catheterization) 以利动物於... doss.tpec.edu.tw|基于6个网页 例句 释义: 全部,前列腺癌细胞 1. Mechanismof themitogen-activatedproteinkinasephosphatase-5regulatingthegrowthandinvasionof ahumanprostateca...