With transrectal prostate biopsies, our patients historically all received a bowel prep with an enema prior to the biopsy as well as antibiotic prophylaxis, meaning IV antibiotics or oral antibiotics prior to the biopsy. Whereas our transperineal prostate biopsies had no bowel prep, no enema, and ...
Intraductal carcinoma of the prostate in prostate biopsy samples: correlation with aggressive pathological features after radical prostatectomy and prognostic value in high-risk prostate cancer. Asian J Androl. 2020;22(5):519–25. Article Google Scholar Zhao T, Liao B, Yao J, Liu J, Huang R,...
Qiagen). The RNAs were processed using the NEB Next Ultra II Directional Library Prep Kit for Illumina (E7765, NEB) and sequenced on the Illumina NextSeq500 with single-end, 75-base-pair-long reads.
we compared a 12-week-old mouse that overexpresses an ARR2Pb driven humanc-MYCtransgene (MYC) in the prostate epithelium to a wild-type (WT) littermate14. At 12 weeks of age, MYC overexpression induces cellular epithelium transformation to PIN, a premalignant condition that often precedes...
The combination gel lubricant is used in a method of performing a transrectal ultra-sound guided needle biopsy.Gary S. Fialk
while RNA integrity was evaluated using the Agilent 2100 Bioanalyzer. The construction of the transcriptome library was performed using the VAHTS Universal V5 RNA-seq Library Prep Kit. The library was sequenced on the Illumina Novaseq 6000 platform. For differential gene expression analysis, the DESeq...
while RNA integrity was evaluated using the Agilent 2100 Bioanalyzer. The construction of the transcriptome library was performed using the VAHTS Universal V5 RNA-seq Library Prep Kit. The library was sequenced on the Illumina Novaseq 6000 platform. For differential gene expression analysis, the DESeq...
A biopsy gun inserts and removes special hollow-core needles (usually three to six on each side of the prostate). The procedure requires a local anaesthetic, and is associated with frequent complications, e.g. bleeding in the urine, bleeding in the stool, blood in the ejaculate and soreness...
However, the patient’s cancer subsequently acquired resistance with rising PSA and subsequent biopsy of a metastatic lymph node showed outgrowth of the clone with BRCA2 loss. It seems that, at this time, the clone with BRCA2 loss dominated, given the >60% decline in his PSA and ...
Metastatic prostate cancer remains a major clinical challenge and metastatic lesions are highly heterogeneous and difficult to biopsy. Liquid biopsy provides opportunities to gain insights into the underlying biology. Here, using the highly sensitive enrichment-based sequencing technology, we provide analysis...