Propylene glycol had no effect on antipyrine half life (11.7 hours control vs. 12.1 hours treatment), clearance (42.6 vs. 39.2 ml/min), or volume of distribution (42.1 vs 41.9 L). At a dose similar to that used as a vehicle for administration of other drugs, propylene glycol had no ...
Propylene glycol has a low degree of toxicity in animals as well as humans, such that very high doses are needed to elicit effects in acute toxicity studies. The toxic effects of propylene glycol appear to be similar in animals and in humans. Central nervous system (CNS) depression, hematolo...
propylene glycol dinitrate is reduced to mononitrates and nitrite, eventually becoming inorganic nitrate. Humans may excrete unmetabolized propylene glycol dinitrate in expired breath following inhalation exposure. Animals have been shown to rapidly excrete propylene glycol dinitrate and its metabolites in ...
308050 PROPYLENE GLYCOL OQEMA With a focus on providing the highest level of service OQEMA has established itself at the forefront of the global chemical industry. The guiding principles of OQEMA have always been to establish long term relationships with customers and suppliers alike to build sustaina...
Propylene glycol methyl ether (PGME) and Propylene glycol methyl ether acetate (PGMEA) [MethylPROXITOL and MethylPROXITOL acetate] Product Stewardship Summary October 2011 Propylene glycol methyl ether (PGME) and Propylene glycol methyl ether acetate (PGMEA) [...
Propylene glycol (PG) is a colorless and odorless liquid chemical used for decades in a wide array of applications. A synthetic substance produced in industrial quantities, it is a relatively simple organic compound that has the chemical formula C3H8O2. The U.S. Food and Drug Administration consi...
Propylene oxideis widely used in the chemical industry as an intermediate in the production of a broad spectrum of materials, such aspolyetherpolyols,propylene glycol, and propylene glycol ethers. These products are further used in the manufacture ofpolyurethane,lubricants, and detergents.Propylene oxid...
Propylene oxide is an excellent low-boiling solvent and raw material of organic synthesis, being able to be used for the preparation of propylene glycol, glycerol, propylene glycol, polyester resin, foam and surfactants. It can also be used as the solvent of cellulose acetate, nitrocellulose and...
Transdermal delivery of naloxone: effect of water, propylene glycol, ethanol and their binary combinations on permeation through rat skin The effect of the solvent systems water, ethanol (EtOH), propylene glycol (PG) and their binary combinations was studied on the ex vivo permeation profile ......
Propylene oxide is an excellent low-boiling solvent and raw material of organic synthesis, being able to be used for the preparation of propylene glycol, glycerol, propylene glycol, polyester resin, foam and surfactants. It can also be used as the solvent of cellulose acetate, nitrocellulose and...