The pharmacokinetics of propranolol were evaluated after repeated oral administration of a new pediatric solution of propranolol at 3 mg kg−1day−1given twice daily (BID) in infants (77‐243 days) withIH. A population model was built to describe the pharmacokinetics of propranolol in ...
英文: PHARMACOKINETICS OF PROPRANOLOL AND ITS METABOLITE 4-HYDROXYPROPRANOLOL中文: 普萘洛尔及其代谢物4-羟普萘洛尔的药代动力学 英文: THE PHARMACOKINETICS OF PROPRANOLOL ENANTIOMERS AND THEIR STEREOSELECTIVE DIFFERENCES中文: 普萘洛尔对映体的药代动力学与立体选择性差异研究 ...
Benzodiazepines:Propranolol causes an increase in the concentration of diazepam and consequently its metabolites. There is no change in the pharmacokinetics of oxazepam, triazolam, lorazepam, and alprazolam when co-administered with Propranolol. Anti-Ulcer Drugs:Cimetidine (non-specific CYP450 inhibitor) w...
Age and gender influence the stereoselective pharmacokinetics of propranolol. The effect of age and gender on the stereoselective pharmacokinetics of propranolol was studied in 12 young (25 to 33 years old) and 12 elderly (62 to 79 years old) healthy nonsmoking volunteers, half of whom were fema...
Pharmacokinetics and Drug Metabolism Distribution Propranolol has a distribution half-life (T1/2 alpha) of 5-10 minutes and a volume of distribution of about 4 to 5 L/kg. Approximately 90% of circulating propranolol is bound to plasma proteins. The binding is enantiomer-selective. The S-iso...
Clinical Pharmacokinetics of Propranolol. Clin-Pharmacokinet 4, 73–90 (1979). https://doi.org/10.2165/00003088-197904020-00001 Download citation Published15 December 2012 Issue DateApril 1979 DOIhttps://doi.org/10.2165/00003088-197904020-00001 Keywords Propranolol Clinical Pharmacology Clinical ...
O'Hare MF, Kinney CD, Murnaghan GA, McDevitt DG (1984) "Pharmacokinetics of propranolol during pregnancy."Eur J Clin Pharmacol, 27, p. 583-7 Levitan AA, Manion JC (1973) "Propranolol therapy during pregnancy and lactation."Am J Cardiol, 32, p. 247 ...
英文: Sex differences in pharmacokinetics of oral propranolol in healthy Chinese volunteers 中文: 口服普萘洛尔在健康中国人药物动力学的性别差异(英文) 更详细... 英文: THE PHARMACOKINETICS OF PROPRANOLOL ENANTIOMERS AND THEIR STEREOSELECTIVE DIFFERENCES 中文: 普萘洛尔对映体的药代动力学与立体选择性差异...
PHARMACOKINETICS1. Single oral 20 mg doses of the HMG-CoA reductase inhibitors pravastatin and lovastatin, with and without concomitant propranolol (40 mg twice daily), were administered to 16 healthy male subjects participating in a randomized, four-way crossover study. 2. Serum concentrations of...
Review of pharmacokinetics: P. A. Routledge, D. G. Shand, Appl. Pharmacokinet. 1980, 464-485; of pharmacology: J. D. Fitzgerald in Pharmacology of Antihypertensive Drugs, A. Scriabine, Ed. (Raven Press, New York, 1980) pp 195-208. Series of articles on use in hypertension: Drugs 37...