As a result, engineering propionyl-CoA metabolism, particularly in genetically tractable hosts with the use of inexpensive feedstocks, has paved an avenue for novel biomanufacturing. Herein, we present a systematic review on manipulation of propionyl-CoA metabolism as well as relevant genetic and ...
Fig. 1. The scheme of propionyl-CoA metabolism. The reported biosynthesis and catabolism of propionyl-CoA in mammalian cells are illustrated in the scheme. Val, valine; Met, methionine; Thr, threonine; Prop, propionate, Odd-chain FAs, odd-chain fatty acids; S-MM-CoA, S-methylmalonyl-CoA; ...
Disorders of propionate and methylmalonate metabolism R. A. Chalmers,A. M. Lawson - 1982 - 被引量: 369 Purification and characterization of 2-methyl-branched chain acyl coenzyme A dehydrogenase, an enzyme involved in the isoleucine and valine metabolism, fro... Y, Ikeda,K, Tanaka - 《Journal...
On the mechanism of action of the antifungal agent propionate: Propionyl-CoA inhibits glucose metabolism in Aspergillus nidulans Brock M, Buckel W (2004) On the mechanism of action of the antifungal agent propionate—propionyl-CoA inhibits glucose metabolism in Aspergillus nidulans ... M Brock,W Bu...
Infantile 'ketotic hyperglycinemia' is an inborn error of metabolism leading to sever protein intolerance, ketoacidosis, and developmental retardation. The biochemical basis for this disorder was obscure until we found in 1969 that peripheral leukocytes form a girl with this condition failed to catabol...
Since acylation is important to the regulation of cellular processes, this may result in broader effects that are not directly related to the “toxic” intermediates or its impact on energy metabolism [89]. 3.7. Propionic acidemia Individuals with classical PA are usually asymptomatic at birth, ...
Role of the methylcitrate cycle in Mycobacterium tuberculosis metabolism, intracellular growth, and virulence. Growth of bacteria and fungi on fatty acid substrates requires the catabolic 尾-oxidation cycle and the anaplerotic glyoxylate cycle. Propionyl-CoA generat... EJ Muñoz-Elías,AM Upton,J Ch...
BICARBONATES CARBON ISOTOPES COENZYME A EXPERIMENTAL LAB STUDY METABOLISM STREPTOMYCES 被引量: 29 年份: 1964 收藏 引用 批量引用 报错 分享 全部来源 求助全文 NCBI NCBI Europe PMC ResearchGate mysciencework.com 相似文献 引证文献The loading domain of the erythromycin polyketide synthase is not essential ...
Propionic acidemia is a diwrder of oqanic acid metabolism caused by a deficiency of propionyl CoA carboxylase (PCC; EC 6,4, activity. PCC requires the covalently bound coenzyme, biotin, to sequentially accept and transfer a carboxyl group from bicarbonate to propionyl CoA, forming D-methylmalonyl...
机译:酰基-CoA定量以及通过天然和茄形青枯菌丙酰基-CoA合成酶的过表达对大肠杆菌聚酮化合物底物的影响。 6. Propionyl Coenzyme A (Propionyl-CoA) Carboxylase in Haloferax mediterranei: Indispensability for Propionyl-CoA Assimilation and Impacts on Global Metabolism [O] . Jing Hou, Hua Xiang, Jing ...