Definite or suspected occupational exposure of healthcare workers to human immunodeficiency virus (HIV) infection is a medical emergency.1 Post-exposure prophylaxis (PEP) with antiretroviral drugs is widely available following such exposure, aiming to prevent HIV infection.1 PEP following non-occupational...
On July 16, 2012, emtricitabine/tenofovir (Truvada; Gilead Sciences) became the first drug approved by the US Food and Drug Administration (FDA) for preexposure prophylaxis (PrEP) of human immunodeficiency virus (HIV) for adults at high risk. Clinical trials have demonstrated that daily use of ...
Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection: Recommendations for a Public Health Approach. 2nd ed. WHO website. https://www.who.int/hiv/pub/arv/arv-2016/en/. Published June 2016. Accessed April 16, 2019. USPSTF Evidence Report: Pre...
Studies examining the use of pre-exposure prophylaxis (PrEP) to prevent HIV transmission among people who inject drugs (PWIDs) have not been adequately summarized. Recently, the Bangkok Tenofovir Study has shown that PrEP may be effective at reducing new HIV infections among this high-risk group...
The potential use of antiretroviral drugs for HIV prophylaxis has been studied extensively in non-human primate models of mucosal and parenteral transmission of SIV or SHIV and, more recently, in a humanized mice model of vaginal HIV transmission (Table 1). Early work in macaques showing that hi...
Antiretroviral drugs for pre-exposure prophylaxis of HIV infection. Though large numberfntiretroviralsaveeen developedorhereatmentfIV infection, newIV infectionsontinueoccur, especiallymongertainigh-risk groups,uchsen whoav... JV Fernández-Montero,P Barreiro,JD Romero,... - 《Aids Reviews》 被引量...
Pre-Exposure Prophylaxis for HIV Prevention in Women: Current Status and Future DirectionsPre-Exposure Prophylaxis for HIV Prevention in Women: Current Status and Future DirectionsHIV preventionPREVENTION of sexually transmitted diseasesTENOFOVIRDRUGSHEALTH...
Management of Sexually Transmitted Infections Other Than HIV Recommendation:Forsexual assaultvictims, clinicians should offer prophylactic medication to prevent gonococcal and chlamydial infections. Routine baseline testing for STIs isnotrecommended in cases of sexual assault. (AIII) ...
HIV/AIDStruvadapreexposure prophylaxisethical challengestreatment vs. preventionequitable distribution of HIV drugsOn July 16, 2012, emtricitabine/tenofovir (Truvada) became the first drug approved by the US Food and Drug Administration for preexposure prophylaxis (PrEP) ofJay, Jonathan...
as the search for potential vaccines and non-antiretroviral microbicides has yielded little result," the WHO guidelines state. "Now, however, a promising new approach has emerged: the use of antiretroviral drugs for HIV prevention, both for those uninfected and for those already living with HIV....