In 1935, Pincus and Enzmann were the first to show that the removal of prophase I arrested rabbit oocytes from their follicular environment resulted in the spontaneous resumption of meiosis (Pincus and Enzmann, 1935). This finding supported a model where the surrounding somatic cells regulated maint...
L. (2013). A Wisp3 Cre-knockin allele produces efficient recombination in spermatocytes during early prophase of meiosis I. PLoS One 8:e75116. doi: 10.1371/journal. pone.0075116S. Hann, L. Kvenvold, B. N. Newby, M. Hong, and M. L. War- man, "A Wisp3 Cre-knockin allele ...
Our data indicate that it is through the differential regulation of the Dacapo that two modes of regulation are independently maintained within the common of . 展开 关键词: oogenesis meiosis dacapo p27 Drosophila cyclin E oocyte differentiation ...
Meiosis is a core event of sexual reproduction. The premeiotic DNA replication followed by meiosis prophase I (MPI) are the first critical stages of the meiotic process. During these stages, the meiotic programme diverges from the mitotic programme, and multiple meiosis-specific features are coordin...
Singa- pore 138673, Republic of Singapore; 3Department of Biochemistry, National University of Singapore (NUS), Singapore 117597, Republic of Singapore A unique feature of female germ cell development in mammals is their remarkably long arrest at the prophase of meiosis I, which lasts up to 50 ...
The pairing of two homologous chromosomes that occurs during meiosis is synapsis (also called syndesis). It enables the matching of homologous pairs and possible chromosomal crossover between them prior to their segregation. This occurs during prophase I of meiosis. ...
ProphaseI is the defining stage of meiosis in that it is unique from mitotic prophase and in that it encompasses many of the I unique features of meiosis, including formation of thesynaptonemal complex(SC), pairing of homologous (maternal and paternal) chromosomes, and formation of chiasmata be...
Therefore, SKP1 maintains synapsis in meiosis of both sexes. Furthermore, our results support a model where SKP1 functions as the long-sought intrinsic metaphase competence factor to orchestrate MI entry during male meiosis. 展开 DOI: 10.1126/sciadv.aaz2129 年份: 2020 ...
MeiosisOocyteSIRT7SirtuinSynapsisSirtuins are NAD+-dependent protein deacylases and ADP-ribosyltransferases that are involved in a wide range of cellular processes including genome homeostasis and metabolism. Sirtuins are expressed in human and mouse oocytes yet their role during female gamete development...
subsequent generations. To achieve this, a diploid cell un-dergoes two rounds of consecutive chromosome segregationduring meiosis, thus giving rise to four haploid products thatcan,inprinciple,developintogametes.Duringthe first meioticdivision, homologous chromosomes are separated from eachother;inthe...