Our findings illustrate that chromosome contact with the nuclear membrane synchronises meiotic progression of the nucleoplasmic chromosomes with that of the cytoplasmic SPB. Keywords: telomeres; meiosis; S. pombe; chromosome; bouquet; Cdc2-Cdc13; Rad3–Chk1; the LINC complex Cell Discovery (2017) ...
During spermatogenesis, meiosis is accompanied by a robust alteration in gene expression and chromatin status. However, it remains elusive how the meiotic transcriptional program is established to ensure completion of meiotic prophase. Here, we identify a protein complex that consists of germ-cell-speci...
Sexually reproducing organisms produce haploid gametes through the specialized cell-division process of meiosis. During meiotic prophase, homologous chromosomes pair and undergo synapsis to enable recombination and crossover formation, which underlie reductional chromosome segregation and genetic variation3,4,5...